Compile Data Set for Download or QSAR
Report error Found 585 Enz. Inhib. hit(s) with Target = 'Glycogen [starch] synthase, liver'
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of insulin-stimulated glycogen synthase in human HepG2 cells using [U-14C]UDP glucose as substrate preincubated for 18 hrs followed by ins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of insulin-stimulated glycogen synthase in human HepG2 cells using [U-14C]UDP glucose as substrate preincubated for 18 hrs followed by ins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635210(US11814367, Compound 659)
Affinity DataIC50: 1.75E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634938(US11814367, Compound 387)
Affinity DataIC50: 3.62E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635119(US11814367, Compound 568 | US11814367, Compound 57...)
Affinity DataIC50: 4.12E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635029(US11814367, Compound 478)
Affinity DataIC50: 6.82E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634926(US11814367, Compound 375)
Affinity DataIC50: 7.74E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634965(US11814367, Compound 414)
Affinity DataIC50: 7.87E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635129(US11814367, Compound 578)
Affinity DataIC50: 7.93E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634919(US11814367, Compound 368)
Affinity DataIC50: 8.23E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634942(US11814367, Compound 391)
Affinity DataIC50: 8.93E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634940(US11814367, Compound 389)
Affinity DataIC50: 9.03E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635135(US11814367, Compound 584)
Affinity DataIC50: 9.18E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635229(US11814367, Compound 678 | US11814367, Compound 68...)
Affinity DataIC50: 9.30E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635119(US11814367, Compound 568 | US11814367, Compound 57...)
Affinity DataIC50: 9.42E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635147(US11814367, Compound 596)
Affinity DataIC50: 9.67E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634552(US11814367, Compound 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634553(US11814367, Compound 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634554(US11814367, Compound 3)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634557(US11814367, Compound 6)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634558(US11814367, Compound 7)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634559(US11814367, Compound 8)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634560(US11814367, Compound 9)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634561(US11814367, Compound 10)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634562(US11814367, Compound 11)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634564(US11814367, Compound 13)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634565(US11814367, Compound 14)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634566(US11814367, Compound 15)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634567(US11814367, Compound 16)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634568(US11814367, Compound 17)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634569(US11814367, Compound 18)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634572(US11814367, Compound 21)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634573(US11814367, Compound 22 | US11814367, Compound 221)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634574(US11814367, Compound 23)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634575(US11814367, Compound 24)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634576(US11814367, Compound 25)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634577(US11814367, Compound 26 | US11814367, Compound 28)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634578(US11814367, Compound 27)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634577(US11814367, Compound 26 | US11814367, Compound 28)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634580(US11814367, Compound 29)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634582(US11814367, Compound 31)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634583(US11814367, Compound 32)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634584(US11814367, Compound 33)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634585(US11814367, Compound 34)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634586(US11814367, Compound 35)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634587(US11814367, Compound 36)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634588(US11814367, Compound 37 | US11814367, Compound 38)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634588(US11814367, Compound 37 | US11814367, Compound 38)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634591(US11814367, Compound 40)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634592(US11814367, Compound 41)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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