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Report error Found 124 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2D'
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50379184(CHEMBL2010868)
Affinity DataEC50:  1.00E+4nMAssay Description:Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  7.80E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2D receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataEC50:  2.80E+3nMAssay Description:Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503152(CHEMBL4452216)
Affinity DataEC50:  2.90E+4nMAssay Description:Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  6.70E+3nMAssay Description:Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50611444(CHEMBL5273123)
Affinity DataEC50:  5.10E+3nMAssay Description:Positive allosteric modulator activity at GluN2D NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
University of Copenhagen

LigandPNGBDBM213888(TK40 | 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]...)
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440060(CHEMBL2426081)
Affinity DataIC50: 170nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440067(CHEMBL2426073 | CHEMBL2426072)
Affinity DataIC50: 190nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440084(CHEMBL2426093)
Affinity DataIC50: 290nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440065(CHEMBL2426075)
Affinity DataIC50: 320nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440085(CHEMBL2426092)
Affinity DataIC50: 390nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440057(CHEMBL2426097)
Affinity DataIC50: 440nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440081(CHEMBL2426096)
Affinity DataIC50: 510nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440077(CHEMBL2425977)
Affinity DataIC50: 530nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440067(CHEMBL2426073 | CHEMBL2426072)
Affinity DataIC50: 570nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440058(CHEMBL2426100)
Affinity DataIC50: 580nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440074(CHEMBL2426065)
Affinity DataIC50: 660nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440052(CHEMBL2426105)
Affinity DataIC50: 690nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440063(CHEMBL2426077)
Affinity DataIC50: 690nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440072(CHEMBL2426067)
Affinity DataIC50: 700nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440073(CHEMBL2426066)
Affinity DataIC50: 810nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440075(CHEMBL2425979)
Affinity DataIC50: 910nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50242446(CHEMBL524338)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50242449(conantokin-G | CHEMBL525025)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50242447(CHEMBL525783)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440051(CHEMBL2425972)
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440076(CHEMBL2425978)
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436102(CHEMBL2397256 | US10273214, Example 1180-26)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436101(CHEMBL2397257 | US10273214, Example 1180-27)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440062(CHEMBL2426078)
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440091(CHEMBL2426086)
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440070(CHEMBL2426068 | CHEMBL2426069)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440078(CHEMBL2426101)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503153(CHEMBL4544421)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436090(CHEMBL2397119 | US10273214, Example 1180-31)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440061(CHEMBL2424674)
Affinity DataIC50: 1.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440050(CHEMBL2425973)
Affinity DataIC50: 1.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440059(CHEMBL2426082)
Affinity DataIC50: 1.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436072(CHEMBL2397211 | US10273214, Example 1426)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440055(CHEMBL2426102)
Affinity DataIC50: 2.30E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503149(CHEMBL4464605)
Affinity DataIC50: 2.40E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440047(CHEMBL2425976)
Affinity DataIC50: 2.60E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50440056(CHEMBL2333944)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of NMDA GluN2D receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50440056(CHEMBL2333944)
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440053(CHEMBL2426104)
Affinity DataIC50: 2.80E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440083(CHEMBL2426094)
Affinity DataIC50: 2.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

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