Compile Data Set for Download or QSAR
Report error Found 2110 Enz. Inhib. hit(s) with Target = 'Galectin-1'
TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768129(US12404295, Example 2.44.106R.)
Affinity DataIC50: 0.0200nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768003((2S,3R,4S,5R,6R)-2-(((R)-(4-Hydroxy-1-methylpiperi...)
Affinity DataIC50: 0.0400nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767974((2S,3R,4S,5R,6R)-2-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.0400nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768024((2S,3R,4S,5R,6R)-2-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768030((2S,3R,4S,5R,6R)-2-(((R)-(3-Cyclopropylpyridin-2-y...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768011((2S,3R,4S,5R,6R)-2-(((4,4-Difluoro-1-hydroxycycloh...)
Affinity DataIC50: 0.0600nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768036(4-((R)-(((2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-(hydroxy...)
Affinity DataIC50: 0.0700nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767973((2S,3R,4S,5R,6R)-2-(((4,4-Difluoro-1-hydroxycycloh...)
Affinity DataIC50: 0.0800nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768138(US12404295, Example 2.44.131R.)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768069(4-Hydroxy-4-((R)-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(h...)
Affinity DataIC50: 0.0900nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768163(US12404295, Example 2.44.131R.I.)
Affinity DataIC50: 0.100nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768072((2R,3R,4S,5R,6S)-6-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.100nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768080((2R,3R,4S,5R,6S)-6-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.100nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768006((2S,3R,4S,5R,6R)-2-(((R)-(4-Hydroxy-1-methylpiperi...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768073((2R,3R,4S,5R,6S)-6-(((R)-(3-Cyclopropylpyridin-2-y...)
Affinity DataIC50: 0.110nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768133(US12404295, Example 2.47.112R.)
Affinity DataIC50: 0.120nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768017((2S,3R,4S,5R,6R)-2-(((5-Cyclopropyl-4-ethylisoxazo...)
Affinity DataIC50: 0.130nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767994((2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(((R)-(4-hydr...)
Affinity DataIC50: 0.130nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768029((2S,3R,4S,5R,6R)-2-(((3-Cyclopropylpyridin-2-yl)(4...)
Affinity DataIC50: 0.140nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768170(US12404295, Example 2.44.105R.I.)
Affinity DataIC50: 0.150nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768000((2S,3R,4S,5R,6R)-2-(((R)-(4-Hydroxy-1-methylpiperi...)
Affinity DataIC50: 0.150nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768139(US12404295, Example 2.49.112R.)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768023((2S,3R,4S,5R,6R)-2-(((4,4-Difluoro-1-hydroxycycloh...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768027((2S,3R,4S,5R,6R)-2-(((R)-(3-Chloropyrazin-2-yl)(4,...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768018((2S,3R,4S,5R,6R)-2-(((R)-(5-Cyclopropyl-4-ethyliso...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768162(US12404295, Example 2.44.130R.I.)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767877((2S,3R,4S,5R,6R)-2-(((R)-2-Hydroxy-1-(2-isopropylp...)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768167(US12404295, Example 24.44.126.I)
Affinity DataIC50: 0.160nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768094((2R,3R,4S,5R,6S)-6-(((4,4-Difluoro-1-hydroxycycloh...)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768038(4-((R)-(((2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-(hydroxy...)
Affinity DataIC50: 0.170nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768079((2R,3R,4S,5R,6S)-6-(((4,4-Difluoro-1-hydroxycycloh...)
Affinity DataIC50: 0.190nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768149(US12404295, Example 2.44.125R.)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768074((2R,3R,4S,5R,6S)-6-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768015((2S,3R,4S,5R,6R)-2-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.200nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767880((2S,3R,4S,5R,6R)-2-(((R)-1-(2-cyclopropylphenyl)-2...)
Affinity DataIC50: 0.210nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767948((2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(((R)-4-hydro...)
Affinity DataIC50: 0.210nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768175(US12404295, Example 2.44.106R.I.)
Affinity DataIC50: 0.210nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768020((2S,3R,4S,5R,6R)-2-(((5-Cyclopropyl-4-isobutylisox...)
Affinity DataIC50: 0.220nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768033((2S,3R,4S,5R,6R)-2-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.220nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768146(US12404295, Example 2.44.119R.)
Affinity DataIC50: 0.230nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767882((2S,3R,4S,5R,6R)-2-((2-Hydroxy-1-(2-isobutylphenyl...)
Affinity DataIC50: 0.240nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768064((2R,3R,4S,5R,6S)-6-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.260nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768044(4-((((2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-(hydroxymeth...)
Affinity DataIC50: 0.270nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768005((2S,3R,4S,5R,6R)-2-(((4-Hydroxy-1-methylpiperidin-...)
Affinity DataIC50: 0.270nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767890((2S,3R,4S,5R,6R)-2-(((R)-1-([1,1'-Biphenyl]-2-yl)-...)
Affinity DataIC50: 0.280nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768131(US12404295, Example 2.39.125R.)
Affinity DataIC50: 0.280nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767876((2S,3R,4S,5R,6R)-2-((2-Hydroxy-1-(2-isopropylpheny...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768012((2S,3R,4S,5R,6R)-2-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM767883((2S,3R,4S,5R,6R)-2-(((R)-2-hydroxy-1-(2-isobutylph...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM768075((2R,3R,4S,5R,6S)-6-(((R)-(4,4-Difluoro-1-hydroxycy...)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/11/2025
Entry Details
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