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Report error Found 1106 Enz. Inhib. hit(s) with Target = 'Fructose-1,6-bisphosphatase 1' Sort by
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataEC50:  16nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305556(N-(5-bromothiazol-2-ylcarbamoyl)-2-ethylbiphenyl-4...)
Affinity DataEC50:  6.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305557(N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridi...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305558(N-(5-bromothiazol-2-ylcarbamoyl)-4-(2-methoxythiaz...)
Affinity DataEC50:  6.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305559(N-(5-bromothiazol-2-ylcarbamoyl)-5-chlorothiophene...)
Affinity DataEC50:  9.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305560(4-bromo-N-(5-bromothiazol-2-ylcarbamoyl)-5-chlorot...)
Affinity DataEC50:  8.70E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305561(N-(5-bromothiazol-2-ylcarbamoyl)-5-methoxy-4-methy...)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305562(N-(5-bromothiazol-2-ylcarbamoyl)-5-isobutyl-4-meth...)
Affinity DataEC50:  1.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305563(N-(5-bromothiazol-2-ylcarbamoyl)-5-(methoxymethyl)...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305564(N-(5-bromothiazol-2-ylcarbamoyl)-5-(hydroxymethyl)...)
Affinity DataEC50:  4.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305565(N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305566(N-(5-bromothiazol-2-ylcarbamoyl)-6,7-dihydro-4H-th...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305567(N-(5-bromothiazol-2-ylcarbamoyl)-5-(3-methoxypropy...)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305568(N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethox...)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305569(N-(5-bromothiazol-2-ylcarbamoyl)-5-(4-methoxy-2-me...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305570(N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-methoxypyrid...)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305571(N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-methoxy-4-me...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305572(N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-fluoropyridi...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305573(N-(5-bromothiazol-2-ylcarbamoyl)-5-methylbenzo[b]t...)
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305574(N-(5-bromothiazol-2-ylcarbamoyl)-1-methyl-1H-indol...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305575(N-(5-bromothiazol-2-ylcarbamoyl)-7-methoxy-1-methy...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305576(N-(5-bromothiazol-2-ylcarbamoyl)-7-(2-hydroxyethox...)
Affinity DataEC50:  6.30E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305577(N-(5-bromo-4-methylthiazol-2-ylcarbamoyl)-3-(diflu...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305578(5-(2-methoxyethyl)-4-methyl-N-(5-(methylthio)thiaz...)
Affinity DataEC50:  6.50E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305579(5-(2-methoxyethyl)-4-methyl-N-(4-methyl-5-(methylt...)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305580(5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(methylt...)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305581(N-(4-ethyl-5-(methylthio)thiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305582(N-(4-ethyl-5-methoxythiazol-2-ylcarbamoyl)-5-(2-hy...)
Affinity DataEC50:  9.20E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305584(N-{[(2Z)-5-BROMO-1,3-THIAZOL-2(3H)-YLIDENE]CARBAMO...)
Affinity DataEC50:  1.18E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305585(N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesu...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305586(N-(5-bromothiazol-2-ylcarbamoyl)-3,5-dimethylbenze...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305587(N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylben...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305588(N-(5-bromothiazol-2-ylcarbamoyl)-2-methylbenzenesu...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesu...)
Affinity DataEC50:  4.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305590(N-(5-bromothiazol-2-ylcarbamoyl)-3-(difluoromethox...)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305591(N-(5-bromothiazol-2-ylcarbamoyl)-3-(trifluorometho...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305592(N-(5-bromothiazol-2-ylcarbamoyl)-3-isopropylbenzen...)
Affinity DataEC50:  7.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305593(3-amino-N-(5-bromothiazol-2-ylcarbamoyl)benzenesul...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305583(N-(5-ethyl-4-methylthiazol-2-ylcarbamoyl)-5-(2-hyd...)
Affinity DataEC50:  8.10E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305594(5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(trifluo...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305595(N-(7-chloro-4-methoxybenzo[d]thiazol-2-ylcarbamoyl...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50504454(CHEMBL4593275)
Affinity DataKd:  5.40E+4nMAssay Description:Binding affinity to human FBPase expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant at 100 uM by UV-visible spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50310094({[(7-carbamoyl-8H-indeno[1,2-d][1,3]thiazol-4-yl)o...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human liver recombinant FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50322036(Ethyl(2S,6S)-4-{[(7-carbamoyl-8H-indeno[1,2-d][1,3...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human FBaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50273103(3-[(3-methylbenzene)sulfonyl]-1-({4-[({[(3-methylb...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphatase in presence of fructose-2,6-bisphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50310095((7-(methylcarbamoyl)-8H-indeno[1,2-d]thiazol-4-ylo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human liver recombinant FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50322037(Ethyl(2S,6S)-2,6-dimethyl-4-({[7-(methylcarbamoyl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FBaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50273103(3-[(3-methylbenzene)sulfonyl]-1-({4-[({[(3-methylb...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50310093((7-(pyrimidin-5-yl)-8H-indeno[1,2-d]thiazol-4-ylox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human liver recombinant FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Boston College

Curated by ChEMBL
LigandPNGBDBM50273102(3-[(3-chlorobenzene)sulfonyl]-1-({4-[({[(3-chlorob...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphatase in presence of fructose-2,6-bisphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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