Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1 [1-336]'
TargetFlap endonuclease 1 [1-336](Human)
University of Sheffield

LigandPNGBDBM197162(3-hydroxy-1-(4-methoxybenzyl)quinazoline-2,4(1H,3H...)
Affinity DataIC50: 16.9nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1 [1-336](Human)
University of Sheffield

LigandPNGBDBM197161(1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,...)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1 [1-336](Human)
University of Sheffield

LigandPNGBDBM50157840(1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-hydr...)
Affinity DataIC50: 46.4nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed