Compile Data Set for Download or QSAR
Report error Found 1964 Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1'
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157851(3''-(3-Hydroxy-2,4-dioxo-3,4-dihydro-2H-thieno[3,2...)
Affinity DataIC50: 0.00300nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157833(N-[3''-(3-Hydroxy-2,4-dioxo-3,4-dihydro-2H-thieno[...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157854(5,6-Dibutyl-3-hydroxy-1H-thieno[2,3-d]pyrimidine-2...)
Affinity DataIC50: 0.00900nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157843(7-Benzenesulfonyl-3-hydroxy-1H-thieno[3,2-d]pyrimi...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157840(1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-hydr...)
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157830(3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)
Affinity DataIC50: 0.0120nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157842(3-Hydroxy-5-methyl-4a,7a-dihydro-1H-thieno[2,3-d]p...)
Affinity DataIC50: 0.0140nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157853(5-Chloro-3-hydroxy-4a,8a-dihydro-1H-quinazoline-2,...)
Affinity DataIC50: 0.0140nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157828(3-Hydroxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157841(7-Biphenyl-4-yl-3-hydroxy-1H-furo[3,2-d]pyrimidine...)
Affinity DataIC50: 0.0230nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157832(3-Hydroxy-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine...)
Affinity DataIC50: 0.0250nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157844(3-Hydroxy-5-methyl-1-phenyl-1H-thieno[2,3-d]pyrimi...)
Affinity DataIC50: 0.0280nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157837(3-Hydroxy-7-(3-methoxy-phenyl)-1H-furo[3,2-d]pyrim...)
Affinity DataIC50: 0.0310nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157838(3-Hydroxy-7-(4-methoxy-phenyl)-1H-furo[3,2-d]pyrim...)
Affinity DataIC50: 0.0340nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157839(3-Hydroxy-1-(4-methoxy-phenyl)-5-methyl-1H-thieno[...)
Affinity DataIC50: 0.0350nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157836(7-Benzyl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50: 0.0380nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157831(3-Hydroxy-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4...)
Affinity DataIC50: 0.0430nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157847(1-(3-Bromo-benzyl)-3-hydroxy-1H-thieno[3,2-d]pyrim...)
Affinity DataIC50: 0.0720nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157845(7-(4-Bromo-phenyl)-3-hydroxy-1H-furo[3,2-d]pyrimid...)
Affinity DataIC50: 0.0760nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)
Affinity DataIC50: 0.0790nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157846(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50: 0.0820nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157835(7-tert-Butyl-3-hydroxy-1H-thieno[3,2-d]pyrimidine-...)
Affinity DataIC50: 0.135nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157829(3-Hydroxy-7-phenyl-1H-furo[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50: 0.143nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157834(3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)
Affinity DataIC50: 0.146nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: 0.230nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157848(3-Hydroxy-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-d...)
Affinity DataIC50: 0.285nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157852(3-Hydroxy-1,5-dimethyl-1H-thieno[2,3-d]pyrimidine-...)
Affinity DataIC50: 0.338nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157849(3''-(3-Hydroxy-7-methyl-2,4-dioxo-3,4-dihydro-2H-t...)
Affinity DataIC50: 1.08nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157830(3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538202(US11253521, No. 72)
Affinity DataIC50: 5.60nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538208(US11253521, No. 78)
Affinity DataIC50: 6.60nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538201(US11253521, No. 71)
Affinity DataIC50: 6.70nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538203(US11253521, No. 73)
Affinity DataIC50: 7.60nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538204(US11253521, No. 74)
Affinity DataIC50: 8.5nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538207(US11253521, No. 77)
Affinity DataIC50: 8.5nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50157832(3-Hydroxy-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine...)
Affinity DataIC50: 9nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538178(US11253521, No. 48)
Affinity DataIC50: 9.30nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538196(US11253521, No. 66)
Affinity DataIC50: 9.30nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538206(US11253521, No. 76)
Affinity DataIC50: 9.40nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538210(US11253521, No. 80)
Affinity DataIC50: 9.40nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538200(US11253521, No. 70)
Affinity DataIC50: 9.80nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538173(US11253521, No. 43)
Affinity DataIC50: 9.90nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538199(US11253521, No. 69)
Affinity DataIC50: 10nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538174(US11253521, No. 44)
Affinity DataIC50: 10.9nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538153(US11253521, No. 23)
Affinity DataIC50: 11nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538180(US11253521, No. 50)
Affinity DataIC50: 11.6nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538205(US11253521, No. 75)
Affinity DataIC50: 11.6nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538187(US11253521, No. 57)
Affinity DataIC50: 12.8nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538188(US11253521, No. 58)
Affinity DataIC50: 12.8nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM538176(US11253521, No. 46)
Affinity DataIC50: 12.9nMAssay Description:Fluorogenic biochemical assays used recombinant full-length FEN-1 or catalytic domains of Exo1, XPG or GEN1 and 200 nM of a DNA substrate (formed by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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