Compile Data Set for Download or QSAR
Report error Found 440 Enz. Inhib. hit(s) with Target = 'Falcipain 2'
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618340(CHEMBL5437384)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of Plasmodium falciparum trophozite extracts FP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618342(CHEMBL5398692)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of Plasmodium falciparum trophozite extracts FP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461249(CHEMBL1215628)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461265(CHEMBL4226307)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50639506(CHEMBL5556412)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to N-terminal 6His-tagged recombinant Plasmodium falciparum FP2 expressed in Escherichia coli M15 assessed as dissociation constant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50243232(N~2~-(MORPHOLIN-4-YLCARBONYL)-N~1~-[(1S,2E)-1-(2-P...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618296(CHEMBL5420328)
Affinity DataIC50: 2nMAssay Description:Inhibition of Plasmodium falciparum Itg2 trophozite extracts FP-2 using Z-phe-Arg-AMC as substrate pretreated with enzyme for 30 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461271(CHEMBL4224764)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461272(CHEMBL4227031)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461269(CHEMBL4227166)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033708(CHEMBL3358129)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618341(CHEMBL5407224)
Affinity DataIC50: 3nMAssay Description:Inhibition of Plasmodium falciparum trophozite extracts FP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461270(CHEMBL4227486)
Affinity DataIC50: 3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50243232(N~2~-(MORPHOLIN-4-YLCARBONYL)-N~1~-[(1S,2E)-1-(2-P...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Plasmodium falciparum Itg2 trophozite extracts FP-2 using Z-phe-Arg-AMC as substrate pretreated with enzyme for 30 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618295(CHEMBL5411543)
Affinity DataIC50: 5nMAssay Description:Inhibition of Plasmodium falciparum Itg2 trophozite extracts FP-2 using Z-phe-Arg-AMC as substrate pretreated with enzyme for 30 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033628(CHEMBL3358142)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461267(CHEMBL4227427)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033761(CHEMBL3358128)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033625(CHEMBL3352874)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461260(CHEMBL4228926)
Affinity DataIC50: 8nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461266(CHEMBL4226577)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of Plasmodium falciparum D10 trophozite lysates FP-2 pretreated with compound for 1 hr followed by labeling with Cy5-DCG04 for 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of FP2' in Plasmodium falciparum trophozoite stage after 1 hr by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033762(Gallinamide A)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of FP2 in Plasmodium falciparum trophozoite stage after 1 hr by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461264(CHEMBL4227848)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033630(CHEMBL3358141)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033626(CHEMBL3358144)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033627(CHEMBL3358143)
Affinity DataIC50: 12nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50322349((R)-Methyl4-(2-(3-((adamantan-1-ylcarbamoyloxy)met...)
Affinity DataKi:  14nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 after 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 15nMAssay Description:Inhibition of falcipain2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 15nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50257018(4-{2-[3-(4-Chloro-2-trifluoromethyl-phenylcarbamoy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 after 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of falcipain-2 in chloroquine sensitive Plasmodium falciparum MRC-02 schizont stage infected in human erythrocytes assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 20nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain 2 expressed in Escherichia coli using Z-Leu-Arg-AMC as substrate incubated for 30 min prior...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461247(CHEMBL4228861)
Affinity DataIC50: 23nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50033659(CHEMBL3358140)
Affinity DataIC50: 25nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461268(CHEMBL4225350)
Affinity DataIC50: 26nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461248(CHEMBL4227295)
Affinity DataIC50: 27nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513155(CHEMBL4434685)
Affinity DataIC50: 29nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513162(CHEMBL4467013)
Affinity DataIC50: 31nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513158(CHEMBL4439637)
Affinity DataIC50: 33nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618332(CHEMBL5426764)
Affinity DataKd:  34nMAssay Description:Binding affinity to Plasmodium falciparum FP-2 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50371561(CHEMBL405741)
Affinity DataKi:  53nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 54nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate incubated for 30 mins by spectrofluorometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461273(CHEMBL4227696)
Affinity DataIC50: 55nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50461256(CHEMBL4228143)
Affinity DataIC50: 57nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513163(CHEMBL4442854)
Affinity DataIC50: 57nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513161(CHEMBL4472824)
Affinity DataIC50: 59nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50513167(CHEMBL4564002)
Affinity DataIC50: 60nMAssay Description:Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Petroleum and Energy Studies

Curated by ChEMBL
LigandPNGBDBM50618339(CHEMBL3218476)
Affinity DataKi:  65nMAssay Description:Inhibition of Plasmodium falciparum FP-2 using Cbz-Leu-Arg-AMC as substrate and measured for 5 to 10 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Displayed 1 to 50 (of 440 total ) | Next | Last >>
Jump to: