Compile Data Set for Download or QSAR
Report error Found 258 Enz. Inhib. hit(s) with Target = 'Estrogen receptor [298-554]'
TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521421(6-(2,4- dichlorophenyl)- 1-fluoro-5-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.400nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521255(3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521262(6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [[(3S)-1-(...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521384(4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.600nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521413(6-(2-fluoro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 0.600nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521382(4-(2-chloro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 0.700nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521428(6-(6-ethoxy-2- fluoro-3- pyridyl)-1- fluoro-5-[6- ...)
Affinity DataIC50: 0.700nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521221(3-(2-fluoro-6- methoxy-3- pyridyl)-4-[4- [(3S)-1-(...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521254(3-(2-fluoro-4- methyl-phenyl)- 4-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521261(6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521334(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521360(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521362(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521369(4-(2,2-difluoro- 1,3- benzodioxol-5- yl)-5-[4-[(3S...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521373(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521374(4-(2,2- dimethylindolin- 5-yl)-5-[4-[(3S)- 1-(3- f...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521377(4-(2,2-dimethyl- 3H-benzofuran- 5-yl)-5-[4-[(3S)- ...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521378(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521381(4-(2,4- dichlorophenyl)- 5-[(6-[(3S)-1-(3- fluorop...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521394(4-[4- (fluoromethoxy) phenyl]-5-[4- [(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521417(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521425(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-1- fluo...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521363(4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [(3S)-1-(3...)
Affinity DataIC50: 1.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521182(7-(2-fluoro-4- hydroxy- phenyl)-8-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521203(3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[4- [(3S)-1-(3...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521229(3-(3-chloro-2- ethoxy-4- pyridyl)-4-[4- [(3S)-1-(3...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521267(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521270(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521295(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521296(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521297(US11149031, Example 189 | 4-(2-fluoro-4- methoxy- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521333(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521345(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521354(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521297(US11149031, Example 189 | 4-(2-fluoro-4- methoxy- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521383(4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521385(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521399(4-(6-amino-2- fluoro-3- pyridyl)-5-[4- [(3S)-1-(3-...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521422(6-(4-ethoxy- 2,3-difluoro- phenyl)-5-[2- [(3S)-1-(...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521361(4-(4-ethoxy-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 2.90nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521202(3-(4-ethoxy-2- fluoro-phenyl)- 4-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521298(4-(2,3- dimethylphenyl)- 5-[4-[(3S)-1-(3- fluoropr...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521303(4-(6-ethoxy-3- pyridyl)-5-[4- [(3S)-1-(3- fluoropr...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521335(4-(2-chloro-4- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521336(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521340(4-(2-fluoro-4- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521341(4-(4-fluoro-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521344(4-(2-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandPNGBDBM521367(4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[4- [...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Displayed 1 to 50 (of 258 total ) | Next | Last >>
Jump to: