Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with Target = 'Epoxide hydrolase B'
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25725(1,3-diphenylurea | Urea-based compound, 7)
Affinity DataIC50: 19nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25725(1,3-diphenylurea | Urea-based compound, 7)
Affinity DataIC50: 19nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant EphB expressed in Escherichia coli BL21 using CMNPC as substrate after 30 mins by fluorescent as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25733(methyl 4-[(adamantan-1-ylcarbamoyl)amino]-2-hydrox...)
Affinity DataIC50: 30nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25732(US8815951, 192 | CHEMBL242255 | 3-adamantan-1-yl-1...)
Affinity DataIC50: 130nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25732(US8815951, 192 | CHEMBL242255 | 3-adamantan-1-yl-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant EphB expressed in Escherichia coli BL21 using CMNPC as substrate after 30 mins by fluorescent as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25728(1,3-bis(4-chlorophenyl)urea | Urea-based compound,...)
Affinity DataIC50: 170nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25730(cid_7547 | US8815951, 3-(4-chlorophenyl)-1-(3,4-di...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant EphB expressed in Escherichia coli BL21 using CMNPC as substrate after 30 mins by fluorescent as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25730(cid_7547 | US8815951, 3-(4-chlorophenyl)-1-(3,4-di...)
Affinity DataIC50: 220nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25731(CHEMBL1458 | 1,3-dicyclohexylurea | US8815951, 1,3...)
Affinity DataIC50: 290nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25727(3-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)urea | U...)
Affinity DataIC50: 460nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25729(US8815951, 299 | CHEMBL10835 | 1,3-bis(3,4-dichlor...)
Affinity DataIC50: 480nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50: 1.96E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25742(1-[4-(4-fluorophenoxy)cyclohexyl]-3-[4-(trifluorom...)
Affinity DataIC50: 2.06E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50: 3.40E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25736(8-[(adamantan-1-ylcarbamoyl)amino]octanoic acid | ...)
Affinity DataIC50: 3.53E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25738(CHEMBL242655 | 1-adamantan-1-yl-3-{5-[2-(2-ethoxye...)
Affinity DataIC50: 8.20E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25741(4-{[4-({[4-(trifluoromethoxy)phenyl]carbamoyl}amin...)
Affinity DataIC50: 1.21E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25735(6-[(adamantan-1-ylcarbamoyl)amino]hexanoic acid | ...)
Affinity DataIC50: 1.67E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 1.85E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25745(3-(1-methanesulfonylpiperidin-4-yl)-1-[4-(trifluor...)
Affinity DataIC50: 2.79E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25744(3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...)
Affinity DataIC50: 3.16E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM50351208(CHEMBL1818421)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant EphB expressed in Escherichia coli BL21 using CMNPC as substrate after 30 mins by fluorescent as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25743(US8501783, 1645 | 1-cycloheptyl-3-(1-acetylpiperid...)
Affinity DataIC50: 3.49E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed