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Report error Found 3771 Enz. Inhib. hit(s) with Target = 'Endothelin-1'
TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279790(Endothelin derivative | CHEMBL414286)
Affinity DataKd:  9.60nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279791(Endothelin derivative | CHEMBL442316)
Affinity DataKd:  0.700nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279795(Endothelin derivative | CHEMBL438027)
Affinity DataKd:  6.60nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50449470(CHEMBL125377)
Affinity DataKd:  3.92E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279787(Endothelin derivative | CHEMBL386629)
Affinity DataKd:  188nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279789(Endothelin derivative | CHEMBL409577)
Affinity DataKd:  17nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279792(Endothelin derivative | CHEMBL412467)
Affinity DataKd:  31nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50000558(Endothelin-1 | ET-1 | Endothelin -1 | c(Cys-Ser-c(...)
Affinity DataKd:  0.150nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279794(Endothelin derivative | CHEMBL438470)
Affinity DataKd:  130nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279796(Endothelin derivative | CHEMBL407887)
Affinity DataKd:  929nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279797(Endothelin derivative | CHEMBL412346)
Affinity DataKd:  52nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279798(Endothelin derivative | CHEMBL410001)
Affinity DataKd:  3.07E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279800(Endothelin derivative | CHEMBL409578)
Affinity DataKd:  4.78E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279801(Endothelin derivative | CHEMBL263581)
Affinity DataKd:  2.10nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50366240(CHEMBL1790883)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279788(Endothelin derivative | CHEMBL409171)
Affinity DataKd:  96nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279803(Endothelin derivative | CHEMBL268318)
Affinity DataKd:  646nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045224(Ac-D-Dip-Leu-Phe-Ile-Ile-Trp | CHEMBL387200)
Affinity DataEC50:  580nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045234(Ac-D-Dip-Leu-Asp-Ile-Ile-Tyr | CHEMBL313344)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045249(Ac-D-Dip-Leu-Asp-Ile-Val-Trp | CHEMBL86703)
Affinity DataEC50:  6.00E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045246(Ac-D-Dip-Orn-Asp-Ile-Ile-Trp | CHEMBL2370066)
Affinity DataEC50:  13nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045256(D-Dip-Leu-Asp-Ile-Ile-Trp | CHEMBL2370067)
Affinity DataEC50:  1.90E+3nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045264(Ac-D-Dip-Leu-Asp-Val-Ile-Trp | CHEMBL315841)
Affinity DataEC50:  17nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50045263(Ac-D-Dip-Glu-Asp-Ile-Ile-Trp | CHEMBL407269)
Affinity DataEC50:  25nMAssay Description:Effective concentration against ET A receptor from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279795(Endothelin derivative | CHEMBL438027)
Affinity DataKd:  1.91E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279788(Endothelin derivative | CHEMBL409171)
Affinity DataKd:  3.12E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279792(Endothelin derivative | CHEMBL412467)
Affinity DataKd:  1.39E+3nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279789(Endothelin derivative | CHEMBL409577)
Affinity DataKd:  0.350nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 1)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279790(Endothelin derivative | CHEMBL414286)
Affinity DataKd:  409nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279791(Endothelin derivative | CHEMBL442316)
Affinity DataKd:  80nMAssay Description:Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand (Exp 2)More data for this Ligand-Target Pair
In DepthDetails Article

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168437(US9675593, 10)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168438(US9675593, 11)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168439(US9675593, 12)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168440(US9675593, 13)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168441(US9675593, 14)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168442(US9675593, 15)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168444(US9675593, 17)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168450(US9675593, 18)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168451(US9675593, 19)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168452(US9675593, 21)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168453(US9675593, 22)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168454(US9675593, 23)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168462(US9675593, 24)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168465(US9675593, 25)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168466(US9675593, 26)
Affinity DataEC50: <5.00E+4nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168467(US9675593, 27)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168468(US9675593, 28)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168469(US9675593, 29)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168470(US9675593, 31)
Affinity DataEC50: <5.00E+4nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelin-1(Human)
Intermune

US Patent
LigandPNGBDBM168471(US9675593, 32)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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