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Report error Found 51 Enz. Inhib. hit(s) with Target = 'Ectonucleoside triphosphate diphosphohydrolase 2'
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50: 10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50: 10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: 10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50187685(CHEMBL597418)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human NTPDase2 expressed in CHO cells using ADP as substrate incubated for 10 mins by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552128(CHEMBL4787368)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human NTPDase2 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511076(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal 6His-tagged recombinant human ENTPD2 (29 to 460 residues) expressed in CHO cells incubated for 30 mins in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50561221(CHEMBL4745473 | US11377469, Example 95)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NTPDase-2 expressed in CHO-K1 cells in presence of DNA/LTX mixtureMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527649(CHEMBL4467828)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 5...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human NTPDase2 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50048062(CHEMBL3314932)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262249(4-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262311(4-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276788(CHEMBL4162261)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276782(CHEMBL4165654)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276783(CHEMBL4169839)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276784(CHEMBL4159530)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276781(CHEMBL4159729)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276789(CHEMBL4175913)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276787(CHEMBL4173693)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276786(CHEMBL4172790)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276794(CHEMBL4161473)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276790(CHEMBL4174849)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276780(CHEMBL4172933)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262252(2-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataIC50: 3.74E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262249(4-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227019(sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50378649(CHEMBL597197)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50048062(CHEMBL3314932)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat recombinant NTPDase2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552129(CHEMBL4744335)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition of rat NTPDase2 expressed in CHO cells using ATP as substrate incubated for 10 mins by UV absorbance methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262311(4-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  2.92E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50227032(acid blue 25 | sodium 1-amino-9,10-dioxo-4-(phenyl...)
Affinity DataKi:  3.58E+4nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262422(sodium (E)-4-((3-formyl-4-hydroxy-5-methyl-2-(phos...)
Affinity DataKi:  4.42E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataKi:  6.54E+4nMAssay Description:Inhibition of rat recombinant NTPDase2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50336799(Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...)
Affinity DataKi:  6.54E+4nMAssay Description:Inhibition of rat NTPDase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262252(2-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  7.17E+4nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262312(2-[2-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  1.16E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262310(3-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  1.67E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262250(4-[3-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  1.73E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50268725(sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50307836(Sodium 1-Amino-4-(2-anthracenylamino)-9,10-dioxo-9...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262251(4-[4-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262373(4-[4-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  2.13E+5nMAssay Description:Inhibition of human NTPDase 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Rat)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50268574(Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10...)
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of rat NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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