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Report error Found 468 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 1' Sort by
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32061(SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...)
Affinity DataIC50: 136nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31044(1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1...)
Affinity DataIC50: 158nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32102(cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...)
Affinity DataIC50: 184nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 190nMAssay Description:The MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay has been Developed and Run at the University of Pittsbur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 197nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31044(1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1...)
Affinity DataIC50: 333nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32102(cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...)
Affinity DataIC50: 423nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50303173(2-(5-((3-(4-(2-chlorobenzyloxy)phenyl)-1-phenyl-1H...)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 485nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50303174(cid_3823393 | CHEMBL584481 | 2-(5-((3-(4-(2-fluoro...)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM32102(cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...)
Affinity DataIC50: 743nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50303175(cid_4050965 | CHEMBL565810 | 2-(5-((3-(4-(benzylox...)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Mouse)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 820nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Mouse)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34163(3-amino-7-benzyl-1-sulfanylidene-6,8-dihydro-5H-th...)
Affinity DataIC50: 1.13E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31040(1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...)
Affinity DataIC50: 1.19E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31044(1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1...)
Affinity DataIC50: 1.24E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34163(3-amino-7-benzyl-1-sulfanylidene-6,8-dihydro-5H-th...)
Affinity DataIC50: 2.38E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50510646(CHEMBL4460074)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM28884(2-[(5Z)-4-oxo-5-({1-phenyl-3-[4-(piperidine-1-sulf...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619701(CHEMBL1575436)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 15(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35361([5-oxido-4-[oxo(thiophen-2-yl)methyl]-1,2,5-oxadia...)
Affinity DataIC50: 3.49E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619701(CHEMBL1575436)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human MKP5 catalytic domain (320 to 467 residues) expressed in Escherichia coli BL21 (DE3) cells by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619703(CHEMBL5418996)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31700(5-[(5-bromanyl-2-methoxy-phenyl)methylidene]-2-(fu...)
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 15(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35407(SMR000019385 | cid_3243550 | 8-[(cyclohexyloxy)car...)
Affinity DataIC50: 4.61E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50510657(CHEMBL4458682)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619709(CHEMBL5393799)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619702(CHEMBL5420188)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35361([5-oxido-4-[oxo(thiophen-2-yl)methyl]-1,2,5-oxadia...)
Affinity DataIC50: 6.39E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31752(cid_1780 | MLS-0002886.0001 | eicosa-5,8,11,14-tet...)
Affinity DataIC50: 6.53E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50510655(CHEMBL4579674)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35361([5-oxido-4-[oxo(thiophen-2-yl)methyl]-1,2,5-oxadia...)
Affinity DataIC50: 6.96E+3nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35361([5-oxido-4-[oxo(thiophen-2-yl)methyl]-1,2,5-oxadia...)
Affinity DataIC50: 6.96E+3nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31700(5-[(5-bromanyl-2-methoxy-phenyl)methylidene]-2-(fu...)
Affinity DataIC50: 7.02E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619710(CHEMBL5427332)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34163(3-amino-7-benzyl-1-sulfanylidene-6,8-dihydro-5H-th...)
Affinity DataIC50: 7.34E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50619704(CHEMBL5396788)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35407(SMR000019385 | cid_3243550 | 8-[(cyclohexyloxy)car...)
Affinity DataIC50: 7.66E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details
PCBioAssay
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50510642(CHEMBL4519826)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35407(SMR000019385 | cid_3243550 | 8-[(cyclohexyloxy)car...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 6His-tagged recombinant MKP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using OMFP as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31734(MLS-0025126.0001 | 8-ethoxycarbonyl-3a,4,5,9b-tetr...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 6His-tagged recombinant MKP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using OMFP as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM31756(cid_646406 | MLS-0007635.0001 | 6,7-dimethyl-3a,4,...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 6His-tagged recombinant MKP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using OMFP as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM50510650(CHEMBL4462328)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
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