Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with Target = 'Double-strand break repair protein MRE11'
TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50633491(CHEMBL5400171)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to his-tagged recombinant human MRE11 assessed as dissociation constant by MST assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572983(US11453663, Preparative Example 160 | 2-cyano-N-(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572770(US11453663, Preparative Example 148 | 3-(2-bromo-3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573122(US11453663, Preparative Example 165 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573124(US11453663, Preparative Example 167 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573125(US11453663, Preparative Example 168 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572574(US11453663, Preparative Example 135 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573128(US11453663, Preparative Example 171 | 2-cyano-N-(4...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573129(US11453663, Preparative Example 172 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573130(US11453663, Preparative Example 173 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573131(US11453663, Preparative Example 174 | 2-cyano-3-(3...)
Affinity DataIC50: 2.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572838(US11453663, Preparative Example 156 | 3-(3-chloro-...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572839(US11453663, Preparative Example 157 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572800(US11453663, Preparative Example 153 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572844(US11453663, Preparative Example 158 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572848(US11453663, Preparative Example 159 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572801(US11453663, Preparative Example 154 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573119(US11453663, Preparative Example 161 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573120(US11453663, Preparative Example 162 | N-(4-(3-chlo...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573121(US11453663, Preparative Example 164 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573123(US11453663, Preparative Example 166 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573127(US11453663, Preparative Example 170 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573132(US11453663, Preparative Example 175 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572799(US11453663, Preparative Example 152 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572527(US11453663, Preparative Example 129 | N-(4-(4-brom...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572528(US11453663, Preparative Example 130 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572537(US11453663, Preparative Example 131 | 2-cyano-N-(4...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572542(US11453663, Preparative Example 132 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572545(US11453663, Preparative Example 133 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572573(US11453663, Preparative Example 134 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572598(US11453663, Preparative Example 136 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572608(US11453663, Preparative Example 137 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572683(US11453663, Preparative Example 138 | N-(4-([1,1&#...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572684(US11453663, Preparative Example 140 | N-(4-(4-(ter...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572707(US11453663, Preparative Example 141 | 2-(3,4-dihyd...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572743(US11453663, Preparative Example 143 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572745(US11453663, Preparative Example 145 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572746(US11453663, Preparative Example 146 | 2-cyano-N-(5...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50044627(Mirin)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of purified recombinant Mre11 exonuclease activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572742(US11453663, Preparative Example 142 | 3-(1H-benzo[...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573126(US11453663, Preparative Example 169 | 2-cyano-3-(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572753(US11453663, Preparative Example 147 | 2-cyano-3-(4...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572771(US11453663, Preparative Example 149 | N-(4-(4-(ter...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572778(US11453663, Preparative Example 151 | 2-cyano-3-(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM572804(US11453663, Preparative Example 155 | 3-(3-chloro-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM573133(US11453663, Preparative Example 179 | 2-cyano-3-(3...)
Affinity DataIC50: 5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDouble-strand break repair protein MRE11(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50044627(Mirin)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of Mre11 exonuclease activity (unknown origin) in cell free extractsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed