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Report error Found 1769 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 9'
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human recombinant DPP9 using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50389480(CHEMBL2063040)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50629038(CHEMBL5425473)
Affinity DataIC50: 1nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM142093(US8933056, Chg-boroPro Thioxamide | US8933056, Chg...)
Affinity DataIC50: 1.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514555(US11096924, DASH-inhibitors 4367 | US11583516, Cmp...)
Affinity DataIC50: 1.5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514555(US11096924, DASH-inhibitors 4367 | US11583516, Cmp...)
Affinity DataIC50: 1.5nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050516(Boronic acid derivative | CHEMBL63726 | US11096924...)
Affinity DataIC50: 1.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 1.70nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50612314(CHEMBL5279548)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of DPP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)
Affinity DataIC50: 1.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50171552((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidine...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50369128(CHEMBL1790483 | US11096924, DASH-inhibitors 4316 |...)
Affinity DataIC50: 2nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50389473(CHEMBL2063033)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514526(US11096924, DASH-inhibitors 5362 | US11583516, Cmp...)
Affinity DataIC50: 2.40nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514526(US11096924, DASH-inhibitors 5362 | US11583516, Cmp...)
Affinity DataIC50: 2.40nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514516(US11096924, DASH-inhibitors 4175 CH | US11583516, ...)
Affinity DataIC50: 2.70nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514516(US11096924, DASH-inhibitors 4175 CH | US11583516, ...)
Affinity DataIC50: 2.70nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM142088(US8933056, Ala-boroPro Thioxamide | US11096924, DA...)
Affinity DataIC50: 2.80nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514518(US11096924, DASH-inhibitors 4317 | US11559537, Com...)
Affinity DataIC50: 3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM142092(US8933056, Val-boroPro Thioxamide | US11096924, DA...)
Affinity DataIC50: 3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50: 3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50629023(CHEMBL5402430)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal human recombinant DPP9 expressed in Sf9 insect cells using Ala-Pro-paranitroanilide as substrate incubated for 15 mins by fl...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50: 3.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050515(Boronic acid derivative | CHEMBL63652 | US11096924...)
Affinity DataIC50: 3.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50389465(CHEMBL2063024)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050521((2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLID...)
Affinity DataIC50: 3.5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514515(US11096924, DASH-inhibitors 3102 C | US11583516, C...)
Affinity DataIC50: 4nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514515(US11096924, DASH-inhibitors 3102 C | US11583516, C...)
Affinity DataIC50: 4nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50629028(CHEMBL5398643)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal human recombinant DPP9 expressed in Sf9 insect cells using Ala-Pro-paranitroanilide as substrate incubated for 15 mins by fl...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50171548((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50243690((2S,4S)-1-((S)-2-amino-6-(naphthalen-2-ylamino)hex...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM12192((2S)-2-amino-2-cyclohexyl-1-(2,3-dihydro-1H-isoind...)
Affinity DataIC50: 4.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50: 4.70nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514545(US11096924, DASH-inhibitors 5333 | US11559537, Com...)
Affinity DataIC50: 5.20nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514554(US11096924, DASH-inhibitors 5363 | US11583516, Cmp...)
Affinity DataIC50: 5.20nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514554(US11096924, DASH-inhibitors 5363 | US11583516, Cmp...)
Affinity DataIC50: 5.20nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514520(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)
Affinity DataIC50: 5.60nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50050527(Boronic acid derivative | CHEMBL66032 | US11096924...)
Affinity DataIC50: 6nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514514(US11096924, DASH-inhibitors (formerly 3102 A 2C) |...)
Affinity DataIC50: 6.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514514(US11096924, DASH-inhibitors (formerly 3102 A 2C) |...)
Affinity DataIC50: 6.10nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50243649((2S,4S)-1-((2S,3R)-2-amino-3-methylpentanoyl)-4-az...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50389471(CHEMBL2063031)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM589767(US11559537, Compound 5322)
Affinity DataIC50: 6.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50171555((S)-2,4-Diamino-1-(2-boron-dihydroxide-pyrrolidin-...)
Affinity DataIC50: 6.70nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 9 using FP-TAMRA incubated for 30 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514532(US11096924, DASH-inhibitors 3102 A | US11583516, C...)
Affinity DataIC50: 7nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM514532(US11096924, DASH-inhibitors 3102 A | US11583516, C...)
Affinity DataIC50: 7nMAssay Description:Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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