Compile Data Set for Download or QSAR
Report error Found 4006 Enz. Inhib. hit(s) with Target = 'Diacylglycerol kinase alpha'
TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679127(US11998539, Example 569 | US11998539, Example 570 ...)
Affinity DataIC50: 0.0700nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678990(US11998539, Example 432 | (rac)-1-methyl-4-[4-meth...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679109(US11998539, Example 551 | 7-[(2-hydroxyethyl)(meth...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679127(US11998539, Example 569 | US11998539, Example 570 ...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651947(US20240051958, Example 18)
Affinity DataIC50: 0.100nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651946(US20240051958, Example 17)
Affinity DataIC50: 0.120nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651949(US20240051958, Example 20)
Affinity DataIC50: 0.130nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651957(US20240051958, Example 28)
Affinity DataIC50: 0.140nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651951(US20240051958, Example 22)
Affinity DataIC50: 0.150nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651944(US20240051958, Example 15)
Affinity DataIC50: 0.190nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678983(US11998539, Example 425 | (rac)-1-methyl-4-[4-(5-m...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679071(US11998539, Example 513 | (rac)-6-bromo-1- methyl-...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679095(US11998539, Example 537 | (−)-6-bromo-1-meth...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679102(US11998539, Example 544 | (rac)-1,6-dimethyl-4-[4-...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679108(US11998539, Example 550 | 7-[(2-hydroxyethyl)amino...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651950(US20240051958, Example 21)
Affinity DataIC50: 0.230nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651952(US20240051958, Example 23)
Affinity DataIC50: 0.270nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678770(US11998539, Example 212 | 7-(methoxymethyl)-1-meth...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678982(US11998539, Example 424 | (rac)-6-bromo-1-methyl-4...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678987(US11998539, Example 429 | (rac)-1,6-dimethyl-4-[4-...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679072(US11998539, Example 514 | (rac)-6-cyano-1-methyl-4...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679102(US11998539, Example 544 | (rac)-1,6-dimethyl-4-[4-...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679106(US11998539, Example 548 | 7-(3-hydroxyazetidin-1-y...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679124(US11998539, Example 566 | 6-chloro-7-methoxy-1-met...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679126(US11998539, Example 568 | (rac)-6-chloro-1-methyl-...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678660(US11998539, Example 102 | 1-methyl-2-oxo-4-(4-{4-[...)
Affinity DataIC50: 0.300nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651953(US20240051958, Example 24)
Affinity DataIC50: 0.310nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651945(US20240051958, Example 16)
Affinity DataIC50: 0.350nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651939(US20240051958, Example 10)
Affinity DataIC50: 0.360nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678773(US11998539, Example 215 | 6-fluoro-1-methyl-4-[4-m...)
Affinity DataIC50: 0.400nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678774(US11998539, Example 216 | 4-[4-(1,3-benzoxazol-2-y...)
Affinity DataIC50: 0.400nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678937(US11998539, Example 379 | US11998539, Example 380 ...)
Affinity DataIC50: 0.400nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679131(US11998539, Example 573 | (rac)-6-chloro-1-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651931(US20240051958, Example 2)
Affinity DataIC50: 0.470nMAssay Description:The DGKA inhibition reactions were performed using ADP-Glo assay. The reactions were carried out in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 1 mM CaCl2...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678854(US11998539, Example 296 | 4-[4-(1,3-benzoxazol-2-y...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678856(US11998539, Example 298 | 6-fluoro-1-methyl-4-[4-(...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678957(US11998539, Example 399 | 7-[(2- hydroxyethyl) (me...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679024(US11998539, Example 466 | 1-methyl-4-{4-[2- methyl...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678726(US11998539, Example 168 | 4-[4-(1,3- benzoxazol-2-...)
Affinity DataIC50: 0.5nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM669109(US11964973, Example 92)
Affinity DataIC50: 0.510nMAssay Description:The DGKα and DGKζ reactions were performed using extruded liposomes (DGKα and DGKζ LIPGLO assays). The reactions were carried out...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678776(US11998539, Example 218 | 4-[4-(1,3-benzoxazol-2-y...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678797(US11998539, Example 239 | 7-[(1-hydroxycyclopropyl...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678855(US11998539, Example 297 | 4-[4-(1,3-benzoxazol-2-y...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678915(US11998539, Example 357 | 1-methyl-4-{4- [(2R)-2-m...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678978(US11998539, Example 420 | 6-bromo-4-[4-fluoro-4-(5...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678986(US11998539, Example 428 | 7-hydroxy-1,6-dimethyl-4...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679072(US11998539, Example 514 | (rac)-6-cyano-1-methyl-4...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679105(US11998539, Example 547 | 7-[(2-methoxyethyl)amino...)
Affinity DataIC50: 0.600nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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