Compile Data Set for Download or QSAR
Report error Found 2161 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1'
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341759(2-Methyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  661nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341761(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341762(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341763(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  534nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341764(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  228nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341765((S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic...)
Affinity DataEC50:  5.66E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341766(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341767((1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbon...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341768(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  216nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341769(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  138nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341770(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  93nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341771(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  410nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341772(5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)a...)
Affinity DataEC50:  219nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341773(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  378nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341774(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  190nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341775(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  165nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341776(N-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)pheny...)
Affinity DataEC50:  362nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341777(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  371nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341778(4-(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  1.76E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341779(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  1.07E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341780(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  2.36E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341781(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  365nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  493nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341783(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  220nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataEC50:  1.44E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  660nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using [14C]palmitic acid by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358323(CHEMBL1922582)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358327(CHEMBL1922676)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358328(CHEMBL1922677)
Affinity DataEC50:  840nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358329(CHEMBL1922678)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358330(CHEMBL1922679)
Affinity DataEC50:  3.70E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358331(CHEMBL1922680)
Affinity DataEC50:  2.99E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358332(CHEMBL1922681)
Affinity DataEC50:  3.42E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358333(CHEMBL1922682)
Affinity DataEC50:  490nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358334(CHEMBL1922683)
Affinity DataEC50:  1.18E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358335(CHEMBL1922684)
Affinity DataEC50:  7.46E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358337(CHEMBL1922686)
Affinity DataEC50:  910nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358338(CHEMBL1922687)
Affinity DataEC50:  1.11E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358339(CHEMBL1922688)
Affinity DataEC50:  8.09E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  660nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358340(CHEMBL1922689)
Affinity DataEC50:  8.90E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50358341(CHEMBL1922690)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50272088(CHEMBL4126883)
Affinity DataEC50:  20nMAssay Description:Inhibition of DGAT1 in human HEK293 cells using [13C18]oleic acid as substrate assessed as decrease in triacylglycerol synthesis preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50272089(CHEMBL4126331)
Affinity DataEC50:  26nMAssay Description:Inhibition of DGAT1 in human HEK293 cells using [13C18]oleic acid as substrate assessed as decrease in triacylglycerol synthesis preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502585(CHEMBL4446248)
Affinity DataEC50:  12nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502588(CHEMBL4439533)
Affinity DataEC50:  206nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502589(CHEMBL4540189)
Affinity DataEC50:  27nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502593(CHEMBL4578901)
Affinity DataEC50:  8nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502594(CHEMBL4475779)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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