Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with Target = 'Delta(24)-sterol reductase'
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278824(CHEMBL4164183)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278863(CHEMBL4174848)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278872(CHEMBL4170755)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278809(CHEMBL4164005)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278822(CHEMBL4167637)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278823(CHEMBL4159728)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278810(CHEMBL4164428)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278807(CHEMBL4167452)
Affinity DataIC50: 198nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278811(CHEMBL4172305)
Affinity DataIC50: 203nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278873(CHEMBL4173086)
Affinity DataIC50: 805nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278832(CHEMBL4162816)
Affinity DataIC50: 823nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278808(CHEMBL4170838)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details Article
PubMed
TargetDelta(24)-sterol reductase(Human)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  3.83E+4nMAssay Description:Binding affinity to human DHCR24 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed