Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase subunit alpha' Sort by
TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733340(US20250115594, Example 11)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733296(US20250115594, Example 9)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733340(US20250115594, Example 11)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733337(US20250115594, Example 12)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733337(US20250115594, Example 12)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733339(US20250115594, Example 8)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733336(US20250115594, Example 10)
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733341(US20250115594, Example 13)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733341(US20250115594, Example 13)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733339(US20250115594, Example 8)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733338(US20250115594, Example 14)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733337(US20250115594, Example 12)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733340(US20250115594, Example 11)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733296(US20250115594, Example 9)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733296(US20250115594, Example 9)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733338(US20250115594, Example 14)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Staphylococcus aureus)
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

US Patent
LigandPNGBDBM733339(US20250115594, Example 8)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50: 120nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50: 170nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50: 210nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50: 220nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50: 220nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50: 290nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466520(US10800725, Compound 8)
Affinity DataIC50: 420nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466524(US10800725, Compound 12)
Affinity DataIC50: 460nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466522(US10800725, Compound 10)
Affinity DataIC50: 530nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466520(US10800725, Compound 8)
Affinity DataIC50: 600nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466515(US10800725, Compound 3)
Affinity DataIC50: 630nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466522(US10800725, Compound 10)
Affinity DataIC50: 640nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466526(US10800725, Compound 14)
Affinity DataIC50: 680nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466515(US10800725, Compound 3)
Affinity DataIC50: 770nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466523(US10800725, Compound 11)
Affinity DataIC50: 780nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466521(US10800725, Compound 9)
Affinity DataIC50: 840nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466523(US10800725, Compound 11)
Affinity DataIC50: 890nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466526(US10800725, Compound 14)
Affinity DataIC50: 1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466517(US10800725, Compound 5)
Affinity DataIC50: 1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466517(US10800725, Compound 5)
Affinity DataIC50: 1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466519(US10800725, Compound 7)
Affinity DataIC50: 1.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466513(US10800725, Compound 1)
Affinity DataIC50: 1.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466518(US10800725, Compound 6)
Affinity DataIC50: 1.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466525(US10800725, Compound 13)
Affinity DataIC50: 1.40E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466516(US10800725, Compound 4)
Affinity DataIC50: 1.60E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466518(US10800725, Compound 6)
Affinity DataIC50: 1.80E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466516(US10800725, Compound 4)
Affinity DataIC50: 1.90E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466513(US10800725, Compound 1)
Affinity DataIC50: 2.10E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466520(US10800725, Compound 8)
Affinity DataIC50: 2.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466522(US10800725, Compound 10)
Affinity DataIC50: 2.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466514(US10800725, Compound 2)
Affinity DataIC50: 2.20E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466515(US10800725, Compound 3)
Affinity DataIC50: 2.40E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466514(US10800725, Compound 2)
Affinity DataIC50: 2.50E+3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

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