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Report error Found 34 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit B'
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470392(CHEMBL4283208)
Affinity DataIC50: 3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470400(CHEMBL4289998)
Affinity DataIC50: 4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470403(CHEMBL4294467)
Affinity DataIC50: 4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470394(CHEMBL4281775)
Affinity DataIC50: 8nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470395(CHEMBL4279313)
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470405(CHEMBL4289650)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470393(CHEMBL4291061)
Affinity DataIC50: 12nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470404(CHEMBL4279382)
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470402(CHEMBL4278317)
Affinity DataIC50: 21nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470399(CHEMBL4286573)
Affinity DataIC50: 23nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470406(CHEMBL4295081)
Affinity DataIC50: 24nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470398(CHEMBL4286232)
Affinity DataIC50: 25nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470396(CHEMBL4293447)
Affinity DataIC50: 49nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50058509(CHEMBL3329317)
Affinity DataIC50: 86nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50393080(CHEMBL2152856)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50173879(CHEMBL3810359)
Affinity DataIC50: 183nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470401(CHEMBL4290062)
Affinity DataIC50: 200nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470397(CHEMBL4294536)
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50006565(CHEMBL3235085)
Affinity DataIC50: 700nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50173878(CHEMBL3809316)
Affinity DataIC50: 746nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058511(CHEMBL3329318)
Affinity DataIC50: 780nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50058510(CHEMBL3329319)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058509(CHEMBL3329317)
Affinity DataIC50: 940nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470407(CHEMBL4286625)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058510(CHEMBL3329319)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 5.38E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50625845(CHEMBL5427814)
Affinity DataIC50: 6.67E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50625842(CHEMBL5419490)
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50625843(CHEMBL5407144)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50550961(CHEMBL4764715)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  12nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50393080(CHEMBL2152856)
Affinity DataKi:  30nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed