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Report error Found 166 Enz. Inhib. hit(s) with Target = 'Cystathionine gamma-lyase'
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human CSE by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280040(CHEMBL1619821)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280013(CHEMBL4163832)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate in presence of 0.01% Triton X-100 by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate in presence of 0.025% Triton X-100 by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280015(CHEMBL4159854)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279931(CHEMBL4166278)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280014(CHEMBL4160453)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280022(CHEMBL4171052)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280026(CHEMBL4162824)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279935(CHEMBL4168463)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280019(CHEMBL4167775)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human CSE by methylene blue methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279998(CHEMBL4166122)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279979(CHEMBL4176894)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279999(CHEMBL4169541)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280025(CHEMBL4170080)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279975(CHEMBL4170257)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280023(CHEMBL4177072)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279932(CHEMBL3318351)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279933(CHEMBL4169868)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279940(CHEMBL4159463)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279943(CHEMBL4160479)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279974(CHEMBL4159631)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279978(CHEMBL4173530)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280012(CHEMBL4174491)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280027(CHEMBL4176749)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by LC/MS/MS-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 6.20E+3nMAssay Description:Non-covalent reversible inhibition of human CSEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50279937(CHEMBL1985550)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50280028(CHEMBL4162997)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50548267(CHEMBL4761159)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CSE using L-Cys as the substrate by tandem well based HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330299(US9725426, 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330300(US9725426, 4)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330307(US9725426, 11)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330308(US9725426, 12)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330309(US9725426, 13)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330311(US9725426, 15)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330316(US9725426, 20)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330317(US9725426, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330318(US9725426, 22)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330319(US9725426, 23)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330320(US9725426, 24)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystathionine gamma-lyase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM330321(US9725426, 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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