Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with Target = 'Complement C3'
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50540845(CHEMBL4642036)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to recombinant human C3d assessed as dissociation constant incubated for 5 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370743(CHEMBL1791380)
Affinity DataKd:  15nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370746(CHEMBL1791381)
Affinity DataKd:  140nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370745(CHEMBL1791382)
Affinity DataKd:  150nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191374(Ac-ICVWQD(5fW)GAHRCT-NH2 | CHEMBL219860)
Affinity DataKd:  35nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191376(Ac-ICV(2Nal)QDWGAHRCT-NH2 | CHEMBL434556)
Affinity DataKd:  110nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370744(CHEMBL1791379)
Affinity DataKd:  120nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191375(Ac-ICV(1MeW)QDWGAHRCT-NH2 | CHEMBL427239)
Affinity DataKd:  17nMAssay Description:Binding affinity to complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50540845(CHEMBL4642036)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to recombinant human C3d assessed as dissociation constant incubated for 5 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50241352(CHEMBL266963 | ICVVQDWGHHRCT-NH2 | 2-[(4R,7S,10S,1...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to complement component C3 in human plasma by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50478748(CHEMBL252927)
Affinity DataKd:  140nMAssay Description:Binding affinity to complement component C3 in human plasma by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50462101(CHEMBL4241221)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to C3b derived from human plasma by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50462096(CHEMBL4247287)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to C3 derived from human plasma by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50462096(CHEMBL4247287)
Affinity DataIC50: 62nMAssay Description:Inhibition of C3 in human serum by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370743(CHEMBL1791380)
Affinity DataIC50: 205nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191375(Ac-ICV(1MeW)QDWGAHRCT-NH2 | CHEMBL427239)
Affinity DataIC50: 205nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191374(Ac-ICVWQD(5fW)GAHRCT-NH2 | CHEMBL219860)
Affinity DataIC50: 446nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159043(Ac-I[CV(2Nal)QDWGAHRC]T-NH2 | CHEMBL427664)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50191376(Ac-ICV(2Nal)QDWGAHRCT-NH2 | CHEMBL434556)
Affinity DataIC50: 545nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159050(Ac-I[CV(Bpa)QDWGAHRC]T-NH2 | CHEMBL430275)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159049(Ac-I[CV(Bta)QDWGAHRC]T-NH2 | CHEMBL439706)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159068(Ac-I[CV(Bta)QDWGAHRC]T | CHEMBL408836)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370744(CHEMBL1791379)
Affinity DataIC50: 870nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159063(Ac-I[CV(Bpa)QDWGAHRC]T | CHEMBL263817)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370746(CHEMBL1791381)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159057(Ac-I[CV(2Igl)QDWGAHRC]T-NH2 | CHEMBL437270)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159069(Ac-I[CV(2Nal)QDWGAHRC]T | CHEMBL437245)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159054(Ac-I[CV(2Igl)QDWGAHRC]T | CHEMBL445418)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159047(Ac-I[CVWQDWG(Abu)HRC]T-NH2 | CHEMBL414282)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50370745(CHEMBL1791382)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of complement C3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159046(Ac-I[CV(1Nal)QDWGAHRC]T | CHEMBL262797)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159071(Ac-I[CVWQDWGAHRC]dT | CHEMBL269247)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159041(Ac-I[CVYQDWGAHRC]T-NH2 | CHEMBL268084)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50070207(CHEMBL3408038)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of C3 cleavage in human serum assessed as reduction in C5b-9 formation compound preincubated for 15 mins measured 1 hr post LPS stimulatio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50070207(CHEMBL3408038)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of C3 cleavage in human serum assessed as reduction in C3b formation compound preincubated for 15 mins measured 1 hr post LPS stimulation ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159066(Ac-I[CVSQDWGHHRC]T-NH2 | CHEMBL415619)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159044(Ac-I[CVTQDWGHHRC]T-NH2 | CHEMBL414283)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159048(Ac-I[CVFQDWGHHRC]T-NH2 | CHEMBL265872)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159060(Ac-I[CVWQDWGWHRC]T-NH2 | CHEMBL415601)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159055(Ac-I[CVWQDWGHHRC]T-NH2 | CHEMBL411957)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159059(Ac-I[CVHQDWGHHRC]T-NH2 | CHEMBL429695)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159067(Ac-I[CV(Yphs)QDWGAHRC]I-NH2 | CHEMBL268083)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159058(Ac-I[CV(Dht)QDWGAHRC]T | CHEMBL437340)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50241352(CHEMBL266963 | ICVVQDWGHHRCT-NH2 | 2-[(4R,7S,10S,1...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of C3 (unknown origin)-binding to convertase of alternative pathway by hemolytic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159037(Ac-I[CVWQDWGAHRC]T | CHEMBL413626)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159064(Ac-I[CVVQDWGAHRC]T-NH2 | CHEMBL269043)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159061(Ac-dI[CVWQDWGAHRC]T | CHEMBL412730)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159040(Ac-I[CVVQDWGHHRC]T-NH2 | CHEMBL409335)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159052(Ac-I[CV(Cha) QDWGAHRC]T | CHEMBL438586)
Affinity DataIC50: 4.78E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C3(Human)
University of California Riverside

Curated by ChEMBL
LigandPNGBDBM50159056(I[CVVQDWGHHRC]T-NH2 | CHEMBL265136)
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibitory concentration for human complement component C3 activationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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