Compile Data Set for Download or QSAR
Report error Found 449 Enz. Inhib. hit(s) with Target = 'Chymotrypsinogen A'
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118029(3-Isopropyl-1-methanesulfonyl-4-(4-piperidin-1-yl-...)
Affinity DataIC50: 22nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058977(3-Benzoyl-1-phenyl-imidazolidine-2,4-dione | CHEMB...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration was measured against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059002(3-(4-Chloro-benzenesulfonyl)-1-(3-chloro-phenyl)-i...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059013(3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50312532(molassamide | CHEMBL1077010)
Affinity DataIC50: 234nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin preincubated for 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | PMSF | Phenylmet...)
Affinity DataIC50: 420nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059011(3-(4-Chloro-benzenesulfonyl)-1-(4-chloro-phenyl)-i...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118030(4-(5-Cyclopropylaminomethyl-pyrazine-2-carbonyl)-3...)
Affinity DataIC50: 540nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058975(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633739(CHEMBL5414337)
Affinity DataIC50: 730nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50: 980nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058997(1-Phenyl-3-(toluene-2-sulfonyl)-imidazolidine-2,4-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059012(3-(4-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50459614(CHEMBL4212843)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate incubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058967(3-(3-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058965(3-[3-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059009(3-Benzenesulfonyl-1-phenyl-imidazolidine-2,4-dione...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50070010(4-((2R,3R)-1-Benzylcarbamoyl-3-methyl-4-oxo-azetid...)
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required to inhibit the mammalian Chymotrypsinogen by 50% was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633738(CHEMBL5431486)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058994(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059007(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633733(CHEMBL5432223)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058964(3-(3,4-Dimethyl-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633736(CHEMBL5394627)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50459616(CHEMBL4217798)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate incubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50065899((2S,3S)-2-Benzyl-3-methylsulfanyl-4-oxo-azetidine-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was tested for its activity against bovine pancreatic Alpha-chymotrypsin (BPC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50085342(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2,3-dime...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50085366(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-methox...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633737(CHEMBL5418049)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633734(CHEMBL5408836)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058998(3-(4-Fluoro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50085356(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(2-methox...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50633735(CHEMBL5397807)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of bovine pancreatic alpha chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate preincubated with enzyme for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50118028(3-Isopropyl-1-methanesulfonyl-4-(2-pyrrolidin-1-yl...)
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50199883(cid_1609 | 3,4-dichloro-1H-isochromen-1-one | CHEM...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using KSp21 as substrate preincubated for 30 mins followed by substrate addition measured after 50 t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50059003(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dichloro-p...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058973(3-(3,4-Dichloro-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50015857(CHEMBL421718 | 3-Acetoxymethyl-5,5,8-trioxo-7-phen...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of alpha-chymotrypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058996(3-(4-Chloro-benzenesulfonyl)-1-(3,4-dichloro-pheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50058971([3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-p...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 4.00E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50085346(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(3,4-dich...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: 4.86E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a pre-incubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM26139(Phenylboronic acid, 11 | 1-benzothiophen-2-ylboran...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM50085361(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(3-hydrox...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChymotrypsinogen A(Bovine)
Gsk

Curated by ChEMBL
LigandPNGBDBM222139(Chymostatin | US11859014, Compound chymostatin)
Affinity DataIC50: 5.80E+3nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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