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Report error Found 224 Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2'
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataKd:  80nMAssay Description:Binding affinity to CERC2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
Affinity DataKd:  77nMAssay Description:Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by BROMOScan analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  8.80nMAssay Description:Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by BROMOScan analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
Affinity DataKd:  200nMAssay Description:Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by VP-ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  187nMAssay Description:Binding affinity to human CECR2 expressed in Escherichia coli L21(DE3)-R3-pRARE2 cells by VP-ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269687(CHEMBL4073178)
Affinity DataEC50:  370nMAssay Description:Binding affinity to ZsGreen fused-CECR2 bromodomain (M404 to H515 residues) (unknown origin) expressed in human U2OS-C433 cells co expressing (MDPKKK...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  570nMAssay Description:Binding affinity to human CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged CECR2 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50503406(CHEMBL4463538)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to recombinant human DNA-tagged CECR2 (423 to 543 residues) expressed in bacterial expression system by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd:  8.20E+3nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514857(CHEMBL4449894)
Affinity DataKd:  25nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataKd:  79nMAssay Description:Binding affinity to CECR2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514858(CHEMBL4577486)
Affinity DataKd:  7.90nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  10nMAssay Description:Binding affinity to CECR2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514856(CHEMBL4465880)
Affinity DataKd:  10nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514899(CHEMBL4461619)
Affinity DataKd:  10nMAssay Description:Binding affinity to CECR2 (unknown origin) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  8nMAssay Description:Reverse ITC (compound as receptor). Domain start/stop: P420-D543More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50573197(CHEMBL4872300)
Affinity DataKd:  11nMAssay Description:Binding affinity to CECR2 (unknown origin) by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <316nMAssay Description:Binding affinity to human CECR2 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50623486(CHEMBL5439294)
Affinity DataKd:  970nMAssay Description:Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by site-directed competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50623487(CHEMBL5398641)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by site-directed competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50623488(CHEMBL5433870)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by site-directed competition binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  8nMAssay Description:Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by site-directed competition binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50615275(CHEMBL5282240)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321437((E)-6-(but-2-en-1-yl)-4-(4-(2-hydroxypropan-2-yl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50615276(CHEMBL5270178)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM321424(6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-...)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514856(CHEMBL4465880)
Affinity DataIC50: 6.30nMAssay Description:Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataIC50: 9.40nMAssay Description:Alphascreen assay. Binding to CECR2A (domain start/stop: P420-H538) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321463(6-(but-3-en-1-yl)-4-(3-(difluoromethoxy)-5-(morpho...)
Affinity DataIC50: 10nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321465(US10183009, Example 57 | 6-but-3-enyl-4-[3-methyl-...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321465(US10183009, Example 57 | 6-but-3-enyl-4-[3-methyl-...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321470(6-but-3-enyl-4-[1-methyl-6-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321476(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321468(6-but-3-enyl-4-[6-(morpholine-4-carbonyl)-1H-benzi...)
Affinity DataIC50: 12nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321474(6-but-3-enyl-4-[4-chloro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 12nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321467(6-but-3-enyl-4-[3-ethyl-7-(morpholine-4-carbonyl)b...)
Affinity DataIC50: 14nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321475(6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 14nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50269687(CHEMBL4073178)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal His6-FLAG-tagged CECR2 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321458(6-but-3-enyl-4-[3,4-difluoro-5-(morpholine-4-carbo...)
Affinity DataIC50: 17nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321459(6-but-3-enyl-4-[3-fluoro-5-(3-methylmorpholine-4-c...)
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50: 19nMAssay Description:Alphascreen assay. Binding to CECR2A (domain start/stop: P420-H538) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321461(6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandPNGBDBM321469(4-(6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[...)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetChromatin remodeling regulator CECR2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50514858(CHEMBL4577486)
Affinity DataIC50: 20nMAssay Description:Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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