Compile Data Set for Download or QSAR
Report error Found 626 Enz. Inhib. hit(s) with Target = 'Chitinase'
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM10854(4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethan...)
Affinity DataIC50: 3.40nMAssay Description:Binding affinity to Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50611491(CHEMBL5290116)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Serratia marcescens chitinase B using MU-(GlcNAc)2 as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetChitinase(Asian corn borer)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  9nMAssay Description:Inhibition of Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50611492(CHEMBL5289869)
Affinity DataIC50: 12nMAssay Description:Inhibition of Serratia marcescens chitinase B using MU-(GlcNAc)2 as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM10854(4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethan...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2006
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50462584(CHEMBL4245260)
Affinity DataIC50: 22nMAssay Description:Inhibition of Serratia marcescens 6x-His-tagged ChiB after 20 hrs by LCMS-SIR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50462584(CHEMBL4245260)
Affinity DataIC50: 22nMAssay Description:Inhibition of Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChitinase A(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257241(N-Ac-D-Ala-Arg{N-omega-(N-methylcarbanoyl)}-N-meth...)
Affinity DataIC50: 25nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase A(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 25nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616562(US20230278996, Example 68.)
Affinity DataIC50: 25nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747826(US12325701, Example 54.)
Affinity DataIC50: 26nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747923(US12325701, Example 151.)
Affinity DataIC50: 30nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM50641175(CHEMBL5572500)
Affinity DataIC50: 32nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50089857(Argadin)
Affinity DataIC50: 33nMAssay Description:Inhibition of Serratia marcescens chitinase ChiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetChitinase-3-like protein 2(Homo sapiens)
Molecure

Curated by ChEMBL
LigandPNGBDBM616505(US20230278996, Example 13.)
Affinity DataIC50: 34nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747837(US12325701, Example 65.)
Affinity DataIC50: 34nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50089847(CHEMBL3577620)
Affinity DataIC50: 36nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616605(US20230278996, Example 111.)
Affinity DataIC50: 36nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747778(US12325701, Example 8.)
Affinity DataIC50: 37nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747807(US12325701, Example 36.)
Affinity DataIC50: 38nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747909(US12325701, Example 137.)
Affinity DataIC50: 48nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616499(US20230278996, Example 8.)
Affinity DataIC50: 50nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  58nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM50641176(CHEMBL5563255)
Affinity DataKd:  59nMAssay Description:Binding affinity to human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells assessed as dissociation constant by bio-layer interferome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616509(US20230278996, Example 17.)
Affinity DataIC50: 78nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM50641173(CHEMBL5565054)
Affinity DataIC50: 82nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase(Asian corn borer)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKd:  85nMAssay Description:Binding affinity to Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetChitinase-3-like protein 2(Homo sapiens)
Molecure

Curated by ChEMBL
LigandPNGBDBM50641167(CHEMBL5563081)
Affinity DataIC50: 90nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase A(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257244(N-Ac-D-Ala-Arg{N-omega-(N-methylcarbanoyl)}-N-meth...)
Affinity DataIC50: 90nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50331851(Allosamidin | CHEMBL1230997)
Affinity DataIC50: 90nMAssay Description:Inhibition of Serratia marcescens chitinase ChiB assessed as reduction in chitinolytic activity using 4MU-(GlcNAc)2 substrate by fluorescence based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50257241(N-Ac-D-Ala-Arg{N-omega-(N-methylcarbanoyl)}-N-meth...)
Affinity DataIC50: 91nMAssay Description:Displacement of 4-methylumbelliferydiacetyl-chitobiose from Serratia marcescens ChiBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616602(US20230278996, Example 108.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616604(US20230278996, Example 110. | US12325701, Example ...)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616598(US20230278996, Example 104.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616599(US20230278996, Example 105.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616600(US20230278996, Example 106.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616600(US20230278996, Example 106.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747927(US12325701, Example 155.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616495(US20230278996, Example 4e. | US12325701, Example 4...)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616496(US20230278996, Example 5. | US12325701, Example 5.)
Affinity DataKd: <100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616497(US20230278996, Example 6b.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616605(US20230278996, Example 111.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747923(US12325701, Example 151.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616606(US20230278996, Example 112.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616494(US20230278996, Example 3g. | US12325701, Example 3...)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616496(US20230278996, Example 5. | US12325701, Example 5.)
Affinity DataKd: <100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent

TargetChitinase B(Serratia marcescens)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to Serratia marcescens chitinase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616589(US20230278996, Example 95.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616494(US20230278996, Example 3g. | US12325701, Example 3...)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM616589(US20230278996, Example 95.)
Affinity DataIC50: 100nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
Go to US Patent

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