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Report error Found 166 Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ'
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81330(+ 1 mM GTP | GTP)
Affinity DataKd:  3.03nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81331(MeGTP (6b))
Affinity DataIC50: 1.00E+4nM Kd:  3.33nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81332(PyrrGTP (7b))
Affinity DataIC50: 1.50E+4nM Kd:  15.6nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataKd:  23nMAssay Description:Displacement of bis-ANS from Escherichia coli FtsZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81336(IGTP (3b))
Affinity DataIC50: 4.40E+4nM Kd:  71nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81333(ClGTP (4b))
Affinity DataIC50: 3.50E+4nM Kd:  77nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81337(tBuGTP (2b))
Affinity DataIC50: 4.10E+4nM Kd:  91nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataKd: <100nMAssay Description:Displacement of free fluorescent probe from inter domain cleft of stabilized Bacillus subtilis FtsZ assessed as dissociation constant in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81335(BrGTP (5b))
Affinity DataIC50: 3.70E+4nM Kd:  126nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus FTsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581034(CHEMBL5085404)
Affinity DataKd:  200nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50589185(CHEMBL5199894)
Affinity DataKd:  600nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581026(CHEMBL5080731)
Affinity DataKd:  700nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Aquifex aeolicus (strain VF5))
University of Amsterdam

LigandPNGBDBM81339(MorphGTP (8b))
Affinity DataIC50: 1.39E+5nM Kd:  714nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581033(CHEMBL5076408)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581024(CHEMBL5092442)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis (strain 168))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079357(CHEMBL3416826)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581029(CHEMBL5085966)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581032(CHEMBL5076150)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581031(CHEMBL5074266)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50402381(CHEMBL2207296)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605151(CHEMBL5188114)
Affinity DataKd:  2.38E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605149(CHEMBL5200927)
Affinity DataKd:  2.49E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FtsZ in Bacillus subtilis assessed as disruption of Z ring formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Escherichia coli recombinant FTsZ incubated for 10 mins in presence of GTP by spectrofluorimeter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50399003(CHEMBL2180486)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581035(CHEMBL5089927)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50399003(CHEMBL2180486)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to Escherichia coli FtsZ at 25 degC by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605150(CHEMBL5174791)
Affinity DataKd:  3.84E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605152(CHEMBL5186593)
Affinity DataKd:  3.86E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM67454(MLS002473304 | purpurin | 1,2,4-tris(oxidanyl)anth...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ assessed as dissociation constant of intrinsic tryptophan quenching incubated for 30 mins by double recipr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50402380(CHEMBL2207300)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylprop-2-enal | cinnamaldehyde | 3-phenylacr...)
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581028(CHEMBL5090219)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50335238(5-Benzamido-2-cyclohexyl-6-N,N-diethylamino-1H-ben...)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581027(CHEMBL5081697)
Affinity DataKd:  6.70E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylprop-2-enal | cinnamaldehyde | 3-phenylacr...)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of Escherichia coli FtsZ polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581036(CHEMBL5092196)
Affinity DataKd:  7.10E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50335239(butyl 2-cyclohexyl-6-(diethylamino)-1H-benzo[d]imi...)
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis FtsZ polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581022(CHEMBL5090793)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50079361(CHEMBL3416824)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50086108(CHEMBL3425702)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581021(CHEMBL5076899)
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50581023(CHEMBL5079700)
Affinity DataKd:  9.50E+3nMAssay Description:Binding affinity to Bacillus subtilis FtsZ polymer assessed as dissociation constant by fluorescence anisotropy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50439495(CHEMBL2418095)
Affinity DataIC50: 9.87E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
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