Compile Data Set for Download or QSAR
Report error Found 163 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 15'
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50296250((S,Z)-3-(2-hydroxy-5-(1-hydroxy-3-methylbutyl)-4-m...)
Affinity DataIC50: 9.31E+4nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25907(BMC173212 Compound 2c | 2-(hydrazinecarbonyl)-3-(4...)
Affinity DataKi:  28nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  30nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  34nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  45nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  45nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50303494(ethyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carbox...)
Affinity DataKi:  46nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25906(2-(hydrazinecarbonyl)-3-(3-methylphenyl)-1H-indole...)
Affinity DataKi:  47nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25913(3-(4-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  47nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25916(BMC173212 Compound 2l | 3-(4-bromophenyl)-2-(hydra...)
Affinity DataKi:  47nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10868(1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...)
Affinity DataKi:  48nM ΔG°:  -41.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10870(aminobenzolamide deriv. 43 | CHEMBL268439 | 2-N-(4...)
Affinity DataKi:  48nM ΔG°:  -41.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25918(BMC173212 Compound 2n | 2-(hydrazinecarbonyl)-3-(2...)
Affinity DataKi:  48nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10868(1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...)
Affinity DataKi:  48nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10869(CHEMBL6753 | 5-imino-4-methyl-4,5-dihydro-1,3,4-th...)
Affinity DataKi:  49nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10871(CHEMBL266026 | 4-amino-N-[(4-sulfamoylphenyl)methy...)
Affinity DataKi:  49nM ΔG°:  -41.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  49nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25917(BMC173212 Compound 2m | 2-(hydrazinecarbonyl)-3-(3...)
Affinity DataKi:  49nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  53nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25909(3-(3-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  54nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25915(BMC173212 Compound 2k | 3-(3-bromophenyl)-2-(hydra...)
Affinity DataKi:  57nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  58nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25911(BMC173212 Compound 2g | 3-(2-chlorophenyl)-2-(hydr...)
Affinity DataKi:  58nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  58nMAssay Description:Inhibition of full length mouse carbonic anhydrase 15 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25908(3-(2-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole...)
Affinity DataKi:  59nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)
Affinity DataKi:  60nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  61nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  61nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10863(4-Amino-3-chlorobenzenesulfonamide | 4-amino-3-chl...)
Affinity DataKi:  62nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  63nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)
Affinity DataKi:  64nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25905(2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole...)
Affinity DataKi:  64nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  65nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  65nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataKi:  66nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25904(BMC173212 Compound 1 | 2-(hydrazinecarbonyl)-3-phe...)
Affinity DataKi:  66nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10873(4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonam...)
Affinity DataKi:  67nM ΔG°:  -40.3kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10865(4-amino-3-iodobenzene-1-sulfonamide | CHEMBL268177...)
Affinity DataKi:  72nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  72nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse recombinant CA15 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of full length mouse carbonic anhydrase 15 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  72nMAssay Description:Inhibition of mouse CA15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM10889(Sulmepride | 2-methoxy-N-[(1-methylpyrrolidin-2-yl...)
Affinity DataKi:  73nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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