Report error Found 1222 Enz. Inhib. hit(s) with Target = 'Calmodulin'
Affinity DataKd: 1.24E+3nMAssay Description:Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysisMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysisMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Experiments were conducted with HITACHI-4500 and Shimadzu RF-5301 fluorescence spectrophotometer.More data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMAssay Description:Experiments were conducted with HITACHI-4500 and Shimadzu RF-5301 fluorescence spectrophotometer.More data for this Ligand-Target Pair
Affinity DataKd: 70nMAssay Description:Experiments were conducted with HITACHI-4500 and Shimadzu RF-5301 fluorescence spectrophotometer.More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Experiments were conducted with HITACHI-4500 and Shimadzu RF-5301 fluorescence spectrophotometer.More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to calmodulin (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to calmodulinMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to calmodulinMore data for this Ligand-Target Pair
Affinity DataKd: 3.40E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 6.10E+4nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
Affinity DataKd: 7.20E+3nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Binding affinity to CaM (unknown origin) by isothermal titration calorimetric analysis in presence of calcium2+More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 7.20E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Inhibition of wild type hemagglutinin-tagged Toxoplasma gondii RH CDPK1 assessed as parasite growth inhibition infected in human foreskin fibroblasts...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataEC50: 470nMAssay Description:Inhibition of wild type hemagglutinin-tagged Toxoplasma gondii RH CDPK1 assessed as parasite growth inhibition infected in human foreskin fibroblasts...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University of Washington Through Its Center For
US Patent
University of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington
Curated by ChEMBL
University of Washington
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
