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Report error Found 17 Enz. Inhib. hit(s) with Target = 'C-C motif chemokine 4'
TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  5.89nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633255(US11458151, Compound MPL | Monophosphoryl Lipid A ...)
Affinity DataEC50:  0.258nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.00100nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633253(US11458151, Compound 3 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  0.0110nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633252(US11458151, Compound 2 | Preparation of 2-[(R)-3-d...)
Affinity DataEC50:  0.0180nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.0580nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633255(US11458151, Compound MPL | Monophosphoryl Lipid A ...)
Affinity DataEC50:  3.10nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N [(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.124nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633253(US11458151, Compound 3 | Preparation of N [(R)-3-D...)
Affinity DataEC50:  0.462nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.251nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM77001(3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoisoin...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM65456(pomalidomide | US9694015, 6.2 | 19171-19-8 | 4-ami...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM76986(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetC-C motif chemokine 4(Human)
Inimmune

US Patent
LigandPNGBDBM77015((R)-3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoi...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In DepthDetails
US Patent