Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 [1-473]'
TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237471(US9393232, 2.46)
Affinity DataIC50: 6.60nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237443(US9393232, 2.16)
Affinity DataIC50: 9.60nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237494(US9393232, 4.1b | US9393232, 4.1a | US9393232, 4.1)
Affinity DataIC50: 18nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237509(US9393232, 2.10b | US9393232, 2.10a)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237521(US9393232, 2.22)
Affinity DataIC50: 32nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237422(US9393232, 1.30a | US9393232, 1.30b)
Affinity DataIC50: 52nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237428(US9393232, 2.2 | US9393232, 2.2b | US9393232, 2.2a)
Affinity DataIC50: 55nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [1-473](Human)
Beigene

US Patent
LigandPNGBDBM237408(US9393232, 1.16)
Affinity DataIC50: 380nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In DepthDetails
US Patent