Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 1'
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataKd:  1.13E+3nMAssay Description:Binding affinity to BRPF2 BRD1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)
Affinity DataKd:  12nMAssay Description:Binding affinity to recombinant human BRPF2 expressed in bacterial system by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataKd:  110nMAssay Description:Binding affinity to BRPF2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataKd:  500nMAssay Description:Binding affinity to BRPF2 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataKd:  210nMAssay Description:Binding affinity to human BRPF2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to human BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged BRD1 expressed in bacterial by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM249277(US9458145, 1020-18 | US10017501, Compound 1020-18)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50514857(CHEMBL4449894)
Affinity DataKd:  126nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd: <1nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50504160(CHEMBL3133807 | US11773085, Compound B25)
Affinity DataKd:  1.65E+3nMAssay Description:Reverse ITC (compound as receptor). Domain start/stop: E556-A688More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50615275(CHEMBL5282240)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM321437((E)-6-(but-2-en-1-yl)-4-(4-(2-hydroxypropan-2-yl)-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50615276(CHEMBL5270178)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM321424(6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50266285(CHEMBL4086276)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataIC50: 48nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 128nMAssay Description:Alphascreen assay. Binding to BRD1A (domain start/stop: E556-A688) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249785(CHEMBL4069814)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249770(CHEMBL4076056)
Affinity DataIC50: 200nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50267005(CHEMBL4099455)
Affinity DataIC50: 230nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249816(CHEMBL4103432)
Affinity DataIC50: 270nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 315nMAssay Description:Alphascreen assay. Binding to BRD1A (domain start/stop: E556-A688) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 440nMAssay Description:Inhibition of BRD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50267003(CHEMBL4081438)
Affinity DataIC50: 450nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50157570(NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...)
Affinity DataIC50: 619nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249810(CHEMBL4102050)
Affinity DataIC50: 760nMAssay Description:Inhibition of human His tagged BRPF2 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50603594(CHEMBL5205457)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged recombinant BRD1 (unknown origin) (11 to 190 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate me...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50158624(CHEMBL3786012)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148468(CHEMBL3769887)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148470(CHEMBL3771002)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249772(CHEMBL4067436)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148463(CHEMBL3770971)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148549(OF-1 | OF 1 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3...)
Affinity DataIC50: 1.68E+3nMAssay Description:Alphascreen assay. Binding to BRD1A (domain start/stop: E556-A688) by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50249771(CHEMBL4070377)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148475(CHEMBL3770465)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148465(CHEMBL3771151)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148478(CHEMBL3769965 | US10702504, Compound A)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50267004(CHEMBL4096095)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148476(CHEMBL3770391)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148460(CHEMBL1346130)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148481(CHEMBL3771005)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148471(CHEMBL3771154)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148473(CHEMBL3770048)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 1(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50148464(CHEMBL3771106)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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