Compile Data Set for Download or QSAR
Report error Found 206 Enz. Inhib. hit(s) with Target = 'Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN'
LigandPNGBDBM646432(US11878973, Example 37)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646438(US11878973, Example 40)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686215(US20240245694, Example 1A | (7R,9R)-6-(4-(4-chloro...)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686219(US20240245694, Example 2A | (7R,9R) N-(2-chloro-4-...)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686227(US20240245694, Example 5A)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686229(US20240245694, Example 6A)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686232(US20240245694, Example 8)
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646369(US11878973, Example 13)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646458(US11878973, Example 50)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646481(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-d...)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686223(US20240245694, Example 3A | (7R,9R) N-(2-chloro-4-...)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686236(US20240245694, Example 12)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686256(US20240245694, Example 21A)
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646351(US11878973, Example 4)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646356(US11878973, Example 66)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646362(US11878973, Example 69)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646383(US11878973, Example 79)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646391(US11878973, Example 81a)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646393(US11878973, Example 81b)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646409(US11878973, Example 89)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646419(US11878973, Example 94)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646427(US11878973, Example 98)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646434(US11878973, Example 38)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646436(US11878973, Example 39)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646440(US11878973, Example 41)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646457(US11878973, Example 113)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646460(US11878973, Example 51)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646462(US11878973, Example 52)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646465(US11878973, Example 117)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686217(US20240245694, Example 1C | (7S,9R)-6-(4-(4-chloro...)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686238(US20240245694, Example 14A)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686246(US20240245694, Example 16)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686252(US20240245694, Example 19A)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686257(US20240245694, Example 21C)
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646345(US11878973, Example 1)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646346(US11878973, Example 61)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646348(US11878973, Example 62)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646354(US11878973, Example 65)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646368(US11878973, Example 72)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646372(US11878973, Example 74)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646374(US11878973, Example 75)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646399(US11878973, Example 84)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646415(US11878973, Example 92)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646421(US11878973, Example 95)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646445(US11878973, Example 107)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM646489(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-d...)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686231(US20240245694, Example 7)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686233(US20240245694, Example 9)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686235(US20240245694, Example 11)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM686237(US20240245694, Example 13)
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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