Compile Data Set for Download or QSAR
Report error Found 876 Enz. Inhib. hit(s) with Target = 'Beta-glucuronidase'
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Affinity DataEC50:  17.7nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataEC50:  233nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Affinity DataEC50:  28.3nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163640(5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7...)
Affinity DataEC50:  92.4nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataEC50:  1.32E+3nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Affinity DataEC50:  811nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163643(2[4(2H1,3benzodioxol5ylmethyl)piperazin1yl]N(2,5di...)
Affinity DataEC50:  777nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataEC50:  3.58nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Affinity DataEC50:  29nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataEC50:  221nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Affinity DataEC50:  33.2nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163640(5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7...)
Affinity DataEC50:  99.9nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataEC50:  1.30E+3nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Affinity DataEC50:  913nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM163643(2[4(2H1,3benzodioxol5ylmethyl)piperazin1yl]N(2,5di...)
Affinity DataEC50:  793nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataEC50:  3.41nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Affinity DataEC50:  18nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50540986(CHEMBL4641364)
Affinity DataEC50:  28nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 0.984nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316366(US9617239, BRITE-354972)
Affinity DataIC50: 1nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 1.17nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50629976(CHEMBL5409470)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human GUSbeta using 4-MUG as substrate pre-incubated for 10 mins followed by substrate addition and measured after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50405568(CHEMBL5273557)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316368(US9617239, BRITE-355252)
Affinity DataIC50: 20nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316459(US9617239, BRITE-492802)
Affinity DataIC50: 30nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316467(US9617239, BRITE-492808)
Affinity DataIC50: 30nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50540970(CHEMBL4638468)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316461(US9617239, BRITE-492805)
Affinity DataIC50: 40nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316468(US9617239, BRITE-492809)
Affinity DataIC50: 40nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316456(US9617239, BRITE-492799)
Affinity DataIC50: 70nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316457(US9617239, BRITE-492800)
Affinity DataIC50: 70nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50540968(CHEMBL4636276)
Affinity DataIC50: 70nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50019283(CHEMBL3289121)
Affinity DataIC50: 70nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316367(US9617239, BRITE-355123)
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316368(US9617239, BRITE-355252)
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316454(US9617239, BRITE-492797)
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50: 100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316460(US9617239, BRITE-492803)
Affinity DataIC50: 100nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50284029(CHEMBL4168635)
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50284071(CHEMBL4165927)
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50: 100nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50541002(CHEMBL4642420 | US12017994, Ref #20')
Affinity DataIC50: 118nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50541002(CHEMBL4642420 | US12017994, Ref #20')
Affinity DataIC50: 118nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50: 120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316369(US9617239, BRITE-354975)
Affinity DataIC50: 120nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316453(US9617239, BRITE-492796)
Affinity DataIC50: 120nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM193734(2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...)
Affinity DataIC50: 120nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM316466(US9617239, BRITE-492807)
Affinity DataIC50: 130nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50540969(CHEMBL4642130)
Affinity DataIC50: 130nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 876 total ) | Next | Last >>
Jump to: