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Report error Found 152 Enz. Inhib. hit(s) with Target = 'Bcl2-associated agonist of cell death'
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to Bcl-XL assessed as inhibition of Bcl-XL-BAD derived peptide interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274325((R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKi:  1.40nMAssay Description:Displacement of fluorescein labeled BAD peptide from Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555339(US11344546, Example 63 | (R)-4-(4-((2-(3-(Difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555340(US11344546, Example 64 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552945(US11344546, Example 67 | (R)-4-(4-((6-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555342(US11344546, Example 69 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555343(US11344546, Example 70 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552934(US11344546, Example 46 | (R)-4-(4-((2-(3-chlorobic...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552931(US11344546, Example 48 | US11590126, Example 48 | ...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552935(US11344546, Example 49 | (R)-4-(4-((4,4-dimethyl-2...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552936(US11344546, Example 50 | (R)-4-(4-((2-(3-Ethylbicy...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555333(US11344546, Example 55 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555334(US11344546, Example 58 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552939(US11344546, Example 59 | (R)-4-(4-((4,4-dimethyl-2...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555336(US11344546, Example 60 | (R)-4-(4-((2-(3-(difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555337(US11344546, Example 61 | (R)-4-(4-((2-(3-(Difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555338(US11344546, Example 62 | (R)-4-(4-((2-(3-(Difluoro...)
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50274315((R)-4-(4-((4'-Chlorobiphenyl-2-yl)methyl)piperazin...)
Affinity DataKi:  14nMAssay Description:Displacement of fluorescein labeled BAD peptide from Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357598(CHEMBL1915449)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50373072(CHEMBL402005)
Affinity DataIC50: 36nMAssay Description:Binding affinity to Bcl-XLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357607(CHEMBL1915641)
Affinity DataEC50:  40nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataEC50:  50nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552931(US11344546, Example 48 | US11590126, Example 48 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM60828(BDBM189459 | US9174982, 369 | ABT-199 | US10213433...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552926(US11318134, Example 36 | BDBM595427 | BDBM555322 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552927(BDBM595428 | BDBM555323 | US11318134, Example 38 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555320(US11344546, Example 34 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataIC50: 55nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM60828(BDBM189459 | US9174982, 369 | ABT-199 | US10213433...)
Affinity DataIC50: 55nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552913(US11344546, Example 17 | US11590126, Example 17 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552930(US11344546, Example 47 | US11590126, Example 47 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataEC50:  90nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555311(US11344546, Example 23 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555312(US11344546, Example 25 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555313(US11344546, Example 26 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555314(US11344546, Example 27 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555315(US11344546, Example 28 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555316(US11344546, Example 30 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555317(US11344546, Example 31 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555318(US11344546, Example 32 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552908(US11344546, Example 10 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552909(US11318134, Example 11 | US11344546, Example 11 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552910(US11344546, Example 13 | US11590126, Example 13 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552911(US11344546, Example 15 | US11590126, Example 15 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552912(US11344546, Example 16 | US11590126, Example 16 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552914(US11344546, Example 20 | US11590126, Example 20 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

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