Compile Data Set for Download or QSAR
Report error Found 212 Enz. Inhib. hit(s) with Target = 'Apolipoprotein L1'
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547875(CHEMBL4754532 | US20230271945, Compound 1)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547876(CHEMBL4791770 | US20230271945, Compound 20)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547877(CHEMBL4795347 | US20230271945, Compound 42)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547878(CHEMBL4752052 | US20230271945, Compound 61)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547879(CHEMBL4780017 | US20230271945, Compound 82)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547880(CHEMBL4789274 | US20230271945, Compound 121)
Affinity DataIC50: 250nMAssay Description:Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547875(CHEMBL4754532 | US20230271945, Compound 1)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547875(CHEMBL4754532 | US20230271945, Compound 1)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615085(US20230271945, Compound 2 | 3-[5,7-difluoro-2-(4-f...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615085(US20230271945, Compound 2 | 3-[5,7-difluoro-2-(4-f...)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615086(3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615086(3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]-...)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615096(US20230271945, Compound 13)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615097(US20230271945, Compound 14)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547876(CHEMBL4791770 | US20230271945, Compound 20)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547876(CHEMBL4791770 | US20230271945, Compound 20)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615102(US20230271945, Compound 21)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615102(US20230271945, Compound 21)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615103(US20230271945, Compound 22)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615104(US20230271945, Compound 23)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615105(US20230271945, Compound 24)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615106(US20230271945, Compound 25)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615107(US20230271945, Compound 26)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615107(US20230271945, Compound 26)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615108(US20230271945, Compound 27)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615108(US20230271945, Compound 27)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615110(US20230271945, Compound 29)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615110(US20230271945, Compound 29)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615111(US20230271945, Compound 30)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615111(US20230271945, Compound 30)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615113(US20230271945, Compound 32)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615115(US20230271945, Compound 34)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615116(US20230271945, Compound 35)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615117(US20230271945, Compound 36)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615117(US20230271945, Compound 36)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615118(US20230271945, Compound 37)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615118(US20230271945, Compound 37)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615119(US20230271945, Compound 38 | US20230271945, Compou...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615121(US20230271945, Compound 40)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615121(US20230271945, Compound 40)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547877(CHEMBL4795347 | US20230271945, Compound 42)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50547877(CHEMBL4795347 | US20230271945, Compound 42)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615124(3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-N-[(3...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615125(3-(5-chloro-2-phenyl-1H-indol-3-yl)-N-[(3S,4R)-4-h...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615125(3-(5-chloro-2-phenyl-1H-indol-3-yl)-N-[(3S,4R)-4-h...)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615126(3-[5-chloro-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(...)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615127(US20230271945, Compound 46)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615127(US20230271945, Compound 46)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615128(US20230271945, Compound 47)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApolipoprotein L1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM615128(US20230271945, Compound 47)
Affinity DataIC50: 600nMAssay Description:Briefly, the AlamarBlue active compound, the resazurin, a blue, water soluble, non-toxic and cell permeable molecule, which can be followed by absorb...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Displayed 1 to 50 (of 212 total ) | Next | Last >>
Jump to: