Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with Target = 'Anthrax toxin receptor 2'
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM175526(US9120744, CDE-002)
Affinity DataIC50: 58nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522442(CHEMBL383306)
Affinity DataIC50: 100nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522441(CHEMBL4557794)
Affinity DataIC50: 132nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522452(CHEMBL4469305)
Affinity DataIC50: 167nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50485547(7-O Methyl Neolambertellin | CHEMBL2070828)
Affinity DataIC50: 500nMAssay Description:Inhibition of AF546-tagged CMG2 R40C mutant binding to AF488-tagged PA E733C mutant incubated for 1 to 3 hrs prior to AF488-tagged PA E733C addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50485548(CHEBI:1369 | CHEMBL559789)
Affinity DataIC50: 600nMAssay Description:Inhibition of AF546-tagged CMG2 R40C mutant binding to AF488-tagged PA E733C mutant incubated for 1 to 3 hrs prior to AF488-tagged PA E733C addition ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 607nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522447(CHEMBL4440070)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522443(CHEMBL4474868)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522450(CHEMBL4570281)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522449(CHEMBL4437267)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522448(CHEMBL4439272)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522446(CHEMBL4521362)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522445(CHEMBL4555734)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522444(CHEMBL4446670)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522451(CHEMBL4463429)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50522453(CHEMBL383459)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AF488-labelled PA binding to AF546- labelled GST-tagged CMG2 R40C/C178A double mutant (unknown origin) expressed in Escherichia coli BL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50056937(3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyloxy)benzoi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM41957(3-[3,4-bis(oxidanyl)phenyl]propanoic acid | 3-(3,4...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50085536(Gallic Acid, F | 3,4,5-Trihydroxybenzoate, X | CHE...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50242283(Methyl protocatechuate | methyl 3,4-dihydroxybenzo...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50187133(Propyl gallate | gallic acid methyl ester | methyl...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50032154(propyl 3,4,5-trihydroxybenzoate | N-Propyl gallate...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50187665((-)-epigallocatechin | CHEMBL47386)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50100861(Protocatechuic acid (M1) | Protocatechuic acid | 3...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM23417(cid_72276 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihyd...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAnthrax toxin receptor 2(Human)
Instituto De Qu£Mica M£Dica (Iqm)

Curated by ChEMBL
LigandPNGBDBM50337364(4-hydroxy-3-methoxybenzoic acid | 4-Hydroxy-3-meth...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed