Report error Found 94 Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3'
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataKd: 7.81E+3nMAssay Description:Binding affinity to recombinant human AlkBH3 incubated for 2 mins by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of ALKBH3 (unknown origin) using 3-methyl cytosine oligo DNA as substrate incubated for 1 hr by SYBR green dye based RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human ALKBH3 by HPLC analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH3 (1 to 286 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release using 40-mer single N3-meC as substrate incubated for 60 mins fo...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Indian Institute of Technology Hyderabad
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysisMore data for this Ligand-Target Pair
