Compile Data Set for Download or QSAR
Report error Found 571 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 1'
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010260(CHEMBL107566 | [2-(2-Bromo-acetylamino)-ethyl]-car...)
Affinity DataKd:  10nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010264(CHEMBL110686 | (2-Isothiocyanato-ethyl)-carbamic a...)
Affinity DataKd:  110nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010259(CHEMBL326463 | Acetic acid 10,10b-dihydroxy-6-{2-[...)
Affinity DataKd:  9nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010263(CHEMBL107985 | Acetic acid 10,10b-dihydroxy-6-(2-i...)
Affinity DataKd:  130nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010267([2-(4-Hydroxy-phenyl)-ethyl]-carbamic acid (3R,4aR...)
Affinity DataKd:  236nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010269(CHEMBL327672 | [2-(4-Hydroxy-phenyl)-ethyl]-carbam...)
Affinity DataKd:  61nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010270(CHEMBL111514 | Acetic acid 6-[2-(2-bromo-acetylami...)
Affinity DataKd:  10nMAssay Description:Binding activity against Adenylate cyclase in bovine brain membrane using [125I]6-IHPP-Fsk as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010272(CHEMBL322952 | {6-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  94nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010271(CHEMBL111425 | {4-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  60nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010266(CHEMBL324659 | {6-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  82nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010273(CHEMBL111738 | {7-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  53nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010274(CHEMBL328561 | Acetic acid (3R,4aR,5S,6S,6aS,10S,1...)
Affinity DataKd:  34nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010265(CHEMBL327142 | {2-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  13nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010275(CHEMBL324463 | {2-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  174nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010262(CHEMBL326703 | {4-[3-(4-Hydroxy-phenyl)-propionyla...)
Affinity DataKd:  80nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010268(CHEMBL91909 | (2-Amino-ethyl)-carbamic acid (3R,4a...)
Affinity DataKd:  98nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Bovine)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50010261(colforsinum | cid_47936 | colforsina | colforsine ...)
Affinity DataKd:  29nMAssay Description:Displacement of [125I]6-IHPP-Fsk from adenylate cyclase of bovine brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052113((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50:  1.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052136(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-Acetoxy-10,1...)
Affinity DataEC50:  3.50E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052111((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50:  3.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052125(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-Trihy...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052127(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052144((2-Hydroxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052119((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataEC50:  2.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052134(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(3,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052132(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052112((3,3-Dimethyl-butyl)-carbamic acid (3R,4aR,5S,6S,6...)
Affinity DataEC50:  9.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052113((2-Methoxy-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052116(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataEC50:  2.70E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052131(Propyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10...)
Affinity DataEC50:  1.30E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataEC50:  6.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052140(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50:  500nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052120(Isobutyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052126((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataEC50:  1.20E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052115((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052148((2-Piperidin-1-yl-ethyl)-carbamic acid (3R,4aR,5S,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052139(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052146((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataEC50:  1.80E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052122(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-10,10...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052134(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(3,...)
Affinity DataEC50:  8.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052145([2-(4-Amino-phenyl)-ethyl]-carbamic acid (3R,4aR,5...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052133(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-cyc...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052149(Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-all...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052138(Allyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10b...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052114(Phenethyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052130((2-Pyridin-2-yl-ethyl)-carbamic acid (3R,4aR,5S,6S...)
Affinity DataEC50:  1.10E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052135((2-Dimethylamino-ethyl)-carbamic acid (3R,4aR,5S,6...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052128(Cyclohexylmethyl-carbamic acid (3R,4aR,5S,6S,6aS,1...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenylate cyclase type 1(Human)
Food and Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052118(Propyl-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10...)
Affinity DataEC50:  4.90E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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