Compile Data Set for Download or QSAR
Report error Found 388 Enz. Inhib. hit(s) with Target = 'Adenosylhomocysteinase'
TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM369458(US10227373, Compound D-Isoneplanocin)
Affinity DataIC50: 0.900nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018507(CHEMBL3290657)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006218((1R,2S,3R)-3-(6-amino-9H-purin-9-yl)cyclopentane-1...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018501(CHEMBL3290650)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018508(CHEMBL3290658)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018533(CHEMBL3290668)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM50140074(CHEMBL2059155 | US10227373, Compound 3-Bromo-3-dea...)
Affinity DataIC50: 2.70nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM50096906(CHEMBL154745 | US10227373, Compound D-3-Deazaisone...)
Affinity DataIC50: 3.19nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050862(CHEMBL3322562)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050862(CHEMBL3322562)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 7.20nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50405728(CHEMBL2115462)
Affinity DataIC50: 8nMAssay Description:Inhibition of S-adenosyl-homocysteine (AdoHcy)hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105901(CHEMBL3597832)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM50465905(CHEMBL4285617)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of SAHase from rabbit erythrocytes using S-adenosyl-L-homocysteine as substrate preincubated for 5 mins followed by substrate addition and...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM369457(US10227373, Compound 3-Deazaneplanocin)
Affinity DataIC50: 9.30nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018514(CHEMBL3290663)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 10nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050877(CHEMBL3322547)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050877(CHEMBL3322547)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 15.2nMAssay Description:Inhibitory effect against S-adenosyl-L-homocysteine hydrolase of rabbit erythrocyte.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 15.2nMAssay Description:Inhibitory activity against S-adenosyl-L-homocysteine hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018508(CHEMBL3290658)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50281613(3-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-5-hydroxyme...)
Affinity DataIC50: 18nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018514(CHEMBL3290663)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Rabbit)
Auburn University

US Patent
LigandPNGBDBM369459(US10227373, Compound L-Isoneplanocin)
Affinity DataIC50: 27nMAssay Description:As a consequence of "D"-Isoneplanocin and "L"-Isoneplanocin, being isomers of Neplanocin A, which on one hand is a potent inhibitor of S-adenosylhomo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018529(CHEMBL3290665)
Affinity DataIC50: 28nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Rat)
Boston College

Curated by ChEMBL
LigandPNGBDBM50316222(D-ERITADENINE | eritadenine | CHEMBL1095280)
Affinity DataIC50: 30nMAssay Description:Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50281612(5-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-3-hydroxyme...)
Affinity DataIC50: 31nMAssay Description:Tested for inhibitory concentration against S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018509(CHEMBL3290659)
Affinity DataIC50: 36nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018507(CHEMBL3290657)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029130(Adenosine dialdehyde | CHEMBL165876)
Affinity DataIC50: 40nMAssay Description:Inhibition of S-adenosyl-homocysteine (AdoHcy)hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018512(CHEMBL3290662)
Affinity DataIC50: 41nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050874(CHEMBL3322550)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050874(CHEMBL3322550)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050868(CHEMBL3322556)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050875(CHEMBL3322549)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050875(CHEMBL3322549)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105907(CHEMBL3597818)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Mouse)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50006222(CHEMBL8771 | (neplanocinA)5-(6-Amino-purin-9-yl)-3...)
Affinity DataIC50: 50nMAssay Description:Evaluated for the 50% inhibition of S-Adenosyl-homocysteine (AdoHcy) hydrolase L929 lysate from murine L-929 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050884(CHEMBL3322540)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050884(CHEMBL3322540)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006218((1R,2S,3R)-3-(6-amino-9H-purin-9-yl)cyclopentane-1...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050869(CHEMBL3322555)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105908(CHEMBL3597817)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050870(CHEMBL3322554)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105899(CHEMBL3597816)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019042(CHEMBL53931 | 3-(6-Amino-purin-9-yl)-5-hydroxymeth...)
Affinity DataIC50: 80nMAssay Description:Inhibition of S-adenosyl-homocysteine (AdoHcy)hydrolase from rabbit erythrocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050883(CHEMBL3322541)
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050883(CHEMBL3322541)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 388 total ) | Next | Last >>
Jump to: