Compile Data Set for Download or QSAR
Report error Found 160 Enz. Inhib. hit(s) with Target = 'ATP-dependent Clp protease proteolytic subunit'
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50028480(CHEMBL3342324)
Affinity DataKd:  300nMAssay Description:Activation of Escherichia coli ClpP by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50028481(CHEMBL3342325)
Affinity DataKd:  700nMAssay Description:Activation of Escherichia coli ClpP by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50360279(CHEMBL1933113)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus NCTC 8325 peptidase activity of clpP expressed in Escherichia coli BL21 after 10 mins using SLY-AMC a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50360280(CHEMBL1933114)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus NCTC 8325 peptidase activity of clpP expressed in Escherichia coli BL21 after 10 mins using SLY-AMC a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50360281(CHEMBL1933116)
Affinity DataEC50:  5.40E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus NCTC 8325 peptidase activity of clpP expressed in Escherichia coli BL21 after 10 mins using SLY-AMC a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535809(Sclerotiamide)
Affinity DataEC50:  3.96E+4nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using Abz-DFAPKMALVPYNO2 as substrate assessed as degradation of substrate peptide preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535810(CHEMBL4593796)
Affinity DataEC50:  2.22E+4nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using FITC-beta casein as substrate assessed as degradation of substrate peptide preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535809(Sclerotiamide)
Affinity DataEC50:  8.75E+4nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using FITC-beta casein as substrate assessed as degradation of substrate peptide preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535811(CHEMBL4549588)
Affinity DataEC50:  100nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using Abz-DFAPKMALVPYNO2 as substrate assessed as degradation of substrate peptide preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535811(CHEMBL4549588)
Affinity DataEC50:  1.20E+3nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using FITC-beta casein as substrate assessed as degradation of substrate peptide preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50535810(CHEMBL4593796)
Affinity DataEC50:  2.54E+4nMAssay Description:Activation of Escherichia coli BLR (DE3) ClpP using Abz-DFAPKMALVPYNO2 as substrate assessed as degradation of substrate peptide preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527098(CHEMBL4446834)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527098(CHEMBL4446834)
Affinity DataEC50:  1.27E+3nMAssay Description:Binding affinity to N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) assessed as shifting o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataEC50:  3.60E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527101(CHEMBL4540126)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527100(CHEMBL4457363)
Affinity DataEC50:  1.48E+4nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527099(CHEMBL4438765)
Affinity DataEC50:  9.60E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50527102(CHEMBL4536802)
Affinity DataEC50:  3.30E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataEC50:  1.99E+4nMAssay Description:Binding affinity to N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) assessed as shifting o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataEC50:  2.35E+4nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50606049(CHEMBL5196543)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50606050(CHEMBL5189726)
Affinity DataEC50:  2.41E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606051(CHEMBL5199237)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606052(CHEMBL5170872)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606053(CHEMBL5188070)
Affinity DataEC50:  660nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606054(CHEMBL5185632)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606055(CHEMBL5176285)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606056(CHEMBL5181638)
Affinity DataEC50:  980nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606057(CHEMBL5194951)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606058(CHEMBL5197677)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606059(CHEMBL5192017)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606060(CHEMBL5181149)
Affinity DataEC50:  1.61E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606061(CHEMBL5195023)
Affinity DataEC50:  3.52E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606062(CHEMBL5174896)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606063(CHEMBL5172475)
Affinity DataEC50:  450nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606064(CHEMBL5197318)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606065(CHEMBL5173519)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606066(CHEMBL5194447)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606067(CHEMBL5193731)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606068(CHEMBL5191830)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606069(CHEMBL5206329)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606070(CHEMBL5181406)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606071(CHEMBL5206788)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606072(CHEMBL5176506)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606073(CHEMBL5170429)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606074(CHEMBL5183001)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606075(CHEMBL5179264)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606076(CHEMBL5193179)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50606077(CHEMBL5180553)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
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