Compile Data Set for Download or QSAR
Report error Found 265 Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6'
LigandPNGBDBM429688(US10550100, Compound 21 | (R)-5-(3-(4-(4- chloro-3...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429689(US10550100, Compound 22 | 5-(3-(4-(4- chloro-3,5- ...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429691(US10550100, Compound 24 | 5-(3-(4-(4- chlorophenyl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429692(US10550100, Compound 25 | 5-(3-(4-(3,5- dichloroph...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429715(US10550100, Compound 36 | 5-(3-(4-(4- chloro-3- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429716(US10550100, Compound 37 | 5-(3-(4-(4- chloro-5- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429723(US10550100, Compound 44 | 5-(3-(4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429724(US10550100, Compound 45 | 5-(3-(4-(3,4- difluoro-5...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429725(US10550100, Compound 46 | (R)-5-(3-(4-(4- chloro-3...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429726(US10550100, Compound 47 | 5-(3-(4-(4- chloro-3- fl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429740(US10550100, Compound 61 | (R)-5-(3-(4- (4,5-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429741(US10550100, Compound 62 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429745(US10550100, Compound 66 | (R)-5-(3-(4-(3- chloro-5...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429747(US10550100, Compound 68 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429748(US10550100, Compound 69 | (R)-5-(3-(4- (3,4-dichlo...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429750(US10550100, Compound 71 | 5-(3-(4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429751(US10550100, Compound 72 | 5-(3-(4-(4- fluoro-3,5- ...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429752(US10550100, Compound 73 | 5-(3-(4-(3- chloro-4- fl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429758(US10550100, Compound 79 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429759(US10550100, Compound 80 | (5R)-5-[3-[4- (3-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429760(US10550100, Compound 81 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429761(US10550100, Compound 82 | (5R)-5-[3-[4- (4-fluoro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429763(US10550100, Compound 84 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429765(US10550100, Compound 85 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429767(US10550100, Compound 87 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429768(US10550100, Compound 88 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429769(US10550100, Compound 89 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429770(US10550100, Compound 90 | (5R)-5-[3-[4- [4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429795(US10550100, Compound 92 | 5-[3-[4-(4,5- dichloro-2...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429771(US10550100, Compound 93 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429797(US10550100, Compound 95 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429772(US10550100, Compound 96 | (5R)-5-[3-[4- (4,5-dichl...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429773(US10550100, Compound 97 | 5-[3-[4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429774(US10550100, Compound 98 | (5R)-5-[3-[4- (4-chloro-...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429776(US10550100, Compound 100 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429778(US10550100, Compound 102 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429779(US10550100, Compound 103 | 5-[3-[4-(4- chloro-3- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429780(US10550100, Compound 104 | 5-[3-[4-(4- chloro-3-et...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429781(US10550100, Compound 105 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429782(US10550100, Compound 106 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429783(US10550100, Compound 107 | 5-[3-[4-(5- chloro-4- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429784(US10550100, Compound 108 | 5-[3-[4-(4- chloro-2- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429785(US10550100, Compound 109 | 5-[3-[4-(4- chloro-5- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429773(US10550100, Compound 97 | 5-[3-[4-(4- chloro-2- me...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429787(US10550100, Compound 111 | 5-[3-[4-(5- chloro-4- f...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429789(US10550100, Compound 113 | 5-[3-[4-(4- chloro-3- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429790(US10550100, Compound 114 | 5-[3-[4-(4- chloro-3- m...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM429791(US10550100, Compound 115 | (5R)-5-[3-[4- (4-chloro...)
Affinity DataIC50: 12.5nMAssay Description:The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM471736(5-cyclopropyl-5- [3-[4-(3,4- difluoro-5- methoxy- ...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM471740((R)-5-[3-[4-(3,4- difluoro-5- methoxy- phenyl) pip...)
Affinity DataIC50: 12.5nMAssay Description:TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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