Compile Data Set for Download or QSAR
Report error Found 272 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1F'
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50573968(CHEMBL4851044)
Affinity DataIC50: 0.320nMAssay Description:Binding affinity to human 5HT1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  1.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130461(LY-334370 | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity at human 5HT1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50106483(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-4...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130461(LY-334370 | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl...)
Affinity DataKi:  1.60nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130461(LY-334370 | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130461(LY-334370 | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl...)
Affinity DataKi:  2.10nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130461(LY-334370 | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl...)
Affinity DataKi:  2.10nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50573975(Lasmiditan | COL-144 | LY573144)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human 5-HT1F assessed as inhibition constant incubated for 10 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50156407(4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indol-6...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50137539(2,4,6-Trifluoro-N-[3-(1-methyl-piperidin-4-yl)-fur...)
Affinity DataKi:  2.30nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130471(1-Methyl-3-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  2.5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50159187(3-Chloro-N-[3-((S)-1-methyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to human 5-hydroxytryptamine 1F receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50137540(2-Chloro-6-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Affinity DataKi:  2.90nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50137538(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-f...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50137541(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-furo[3,2-b...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50091438((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-i...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50156409(2-Chloro-4-fluoro-N-[3-(1-methyl-piperidin-4-yl)-b...)
Affinity DataKi:  3.60nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130422(1-Ethyl-3-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[...)
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50106484(N-[3-(2-Dimethylamino-ethyl)-1H-indol-4-yl]-4-fluo...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50156410(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indazol...)
Affinity DataKi:  3.90nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50106249([2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethyl]-dimeth...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 1F receptor in CHO cells using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  3.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50156411(4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-1H-indazol...)
Affinity DataKi:  4.10nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130468(2,4-Dichloro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyr...)
Affinity DataKi:  4.10nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130439(Furan-3-carboxylic acid [3-(1-methyl-piperidin-4-y...)
Affinity DataKi:  4.60nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130466(Methanesulfonic acid 3-(1-methyl-piperidin-4-yl)-1...)
Affinity DataKi:  4.70nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50573966(CHEMBL4847626)
Affinity DataIC50: 4.70nMAssay Description:Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50156404(4-Fluoro-N-[1-(1-methyl-piperidin-4-yl)-2,3-dihydr...)
Affinity DataKi:  4.80nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130448(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130448(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  5nMAssay Description:Binding affinity to 5-HT1F (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50119543(CHEMBL3617549)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130426(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  5.5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130426(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to 5-HT1F (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130436(3-Methyl-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  5.80nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataEC50:  6nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50590656(LY-344864 | CHEMBL1628565)
Affinity DataKi:  6nMAssay Description:Binding affinity to human 5-HT1F assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM85195(NSC_5311097 | CAS_5311097 | LY 344864)
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Mouse)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50031942(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130442(Pyridine-2-carboxylic acid [3-(1-methyl-piperidin-...)
Affinity DataKi:  6.30nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50573964(CHEMBL4846825)
Affinity DataIC50: 6.40nMAssay Description:Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130465(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  6.90nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130467(Thiophene-2-carboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  7.10nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130432(4-Cyano-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[...)
Affinity DataKi:  7.20nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130445(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  7.30nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130447(Thiophene-3-carboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  7.40nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130463(4-Fluoro-benzenesulfonic acid 3-(1-methyl-piperidi...)
Affinity DataKi:  7.5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50130451(N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]py...)
Affinity DataKi:  7.70nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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