Report error Found 2944 Enz. Inhib. hit(s) with Target = '5'-nucleotidase'
Affinity DataEC50: 51nMAssay Description:Inhibition of CD73 in human serum using 13C5-15N5-AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 15 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 213nMAssay Description:Inhibition of CD73 in human serum using 13C5-15N5-AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 15 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Inhibition of CD73 in human CD8+ T-cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and me...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.63E+4nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Affinity DataEC50: 6.90nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and meas...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and meas...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and meas...More data for this Ligand-Target Pair
Affinity DataEC50: 198nMAssay Description:Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00270nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Affinity DataIC50: 0.00850nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0130nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0270nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0310nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0310nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0320nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of soluble human CD73More data for this Ligand-Target Pair
Affinity DataIC50: 0.0450nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of human CD73 expressed in A-375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0520nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of soluble human CD73More data for this Ligand-Target Pair
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0740nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0950nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CD73 in human plasma derived from esophageal cancer patient incubated for 15 mins in presence of 15N5-AMP by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.115nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:I. Experimental Materials and Equipment1. Malachite green phosphate detection kit (R & D Systems, Cat #, DY996)2. Recombinant human 5′-nucleoti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 0.140nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
