Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [51-359,V143T]'
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM2691(Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed