Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with Target = '2-hydroxyacylsphingosine 1-beta-galactosyltransferase'
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in GalCer accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in SFT accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561669(CHEMBL4787939)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561671(CHEMBL4796521)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561671(CHEMBL4796521)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561670(CHEMBL4750073)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561669(CHEMBL4787939)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561664(CHEMBL4776963)
Affinity DataIC50: 1nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561670(CHEMBL4750073)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561672(CHEMBL4750432)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561663(CHEMBL4765010)
Affinity DataIC50: 2nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561663(CHEMBL4765010)
Affinity DataIC50: 2nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561672(CHEMBL4750432)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561664(CHEMBL4776963)
Affinity DataIC50: 3nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561665(CHEMBL4755797)
Affinity DataIC50: 18nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561665(CHEMBL4755797)
Affinity DataIC50: 37nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561667(CHEMBL4757982)
Affinity DataIC50: 43nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561667(CHEMBL4757982)
Affinity DataIC50: 48nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561655(CHEMBL4760937)
Affinity DataIC50: 67nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561655(CHEMBL4760937)
Affinity DataIC50: 90nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561657(CHEMBL4795937)
Affinity DataIC50: 97nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561657(CHEMBL4795937)
Affinity DataIC50: 120nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561658(CHEMBL4799472)
Affinity DataIC50: 170nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561662(CHEMBL4797076)
Affinity DataIC50: 190nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561668(CHEMBL4764180)
Affinity DataIC50: 200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561661(CHEMBL4751927)
Affinity DataIC50: 200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561656(CHEMBL4747085)
Affinity DataIC50: 320nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561661(CHEMBL4751927)
Affinity DataIC50: 330nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561662(CHEMBL4797076)
Affinity DataIC50: 350nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561658(CHEMBL4799472)
Affinity DataIC50: 360nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561659(CHEMBL4745037)
Affinity DataIC50: 450nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561673(CHEMBL4799203)
Affinity DataIC50: 510nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561660(CHEMBL4791074)
Affinity DataIC50: 610nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561666(CHEMBL4762406)
Affinity DataIC50: 610nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561656(CHEMBL4747085)
Affinity DataIC50: 640nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561659(CHEMBL4745037)
Affinity DataIC50: 660nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561674(CHEMBL4752928)
Affinity DataIC50: 980nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50561660(CHEMBL4791074)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed