Report error Found 131 Enz. Inhib. hit(s) with Target = '2-5A-dependent ribonuclease'
Affinity DataEC50: 241nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Activation of human recombinant RNase L endonuclease activity using 6-FAM-UUA UCA AAU UCU UAU UUG CCC CAU UUU UUU GGU UUA-BHQ-1 as substrate assessed...More data for this Ligand-Target Pair
Affinity DataEC50: 0.240nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Binding affinity of compound to human recombinant Ribonuclease L was evaluatedMore data for this Ligand-Target Pair
Affinity DataEC50: 0.840nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 393nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 323nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 396nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Activation of mouse RNase L assessed as ability to cleave 5'-[32P]r(C11U2C7)More data for this Ligand-Target Pair
Affinity DataEC50: 0.450nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 134nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 84nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...More data for this Ligand-Target Pair
Affinity DataEC50: 9.70nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
Affinity DataEC50: >50nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
Affinity DataEC50: >50nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Inhibition of human RNaseL ANK domain expressed in Escherichia coli assessed as 5' flurescein-r(C11U2C7)-3' RNA cleavageMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 9.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+4nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+4nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
Affinity DataKd: 0.0400nMAssay Description:Binding affinity to human recombinant RNase LMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probeMore data for this Ligand-Target Pair
Affinity DataKd: 0.220nMAssay Description:Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonanceMore data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
Affinity DataEC50: 4.60nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
