Report error Found 68 Enz. Inhib. hit(s) with Target = '1-deoxy-D-xylulose-5-phosphate synthase'
Displayed 1 to 50 (of 68 total ) | Next | Last >>
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Mouse-ear cress)
Basf-Se
Curated by ChEMBL
Basf-Se
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Deinococcus radiodurans (strain ATCC 13939 / DSM 2...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKd: 114nMAssay Description:Binding affinity to Deinococcus radiodurans DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (G-proteobacteria))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Haemophilus influenzae recombinant DXPSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (G-proteobacteria))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (G-proteobacteria))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.10E+3nMAssay Description:Uncompetitive inhibition of Escherichia coli DXPS assessed as inhibition constant in presence of fixed concentration of GAP and varying concentration...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 5.60E+3nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.60E+3nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.80E+3nMAssay Description:Mixed non-competitive inhibition of Escherichia coli DXPS assessed as inhibition constant in presence of fixed concentration of pyruvate and varying ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Competitive inhibition of ThDP-dependent Escherichia coli DXP synthase using pyruvate as substrate assessed as NADPH consumption by spectrophotometri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Uncompetitive inhibition of Escherichia coli DXPS assessed as inhibition constant in presence of fixed concentration of pyruvate and varying concentr...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli O127:H6 (strain E2348/69 / EPEC))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 1.04E+4nMAssay Description:Inhibition of Escherichia coli DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (G-proteobacteria))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataKi: 2.33E+4nMAssay Description:Inhibition of Haemophilus influenzae DXSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Haemophilus influenzae (G-proteobacteria))
University of Cambridge
Curated by ChEMBL
University of Cambridge
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Haemophilus influenzae recombinant DXPSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Mouse-ear cress)
Basf-Se
Curated by ChEMBL
Basf-Se
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Mouse-ear cress)
Basf-Se
Curated by ChEMBL
Basf-Se
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Mouse-ear cress)
Basf-Se
Curated by ChEMBL
Basf-Se
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 5.51E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic(Mouse-ear cress)
Basf-Se
Curated by ChEMBL
Basf-Se
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Arabidopsis thaliana N-terminal GST-tagged DXS expressed in Escherichia coli BL21 GOLD (DE) using glyceraldehydephosphate and pyruvate ...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 6.37E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 7.50E+4nMAssay Description:Inhibition of Escherichia coli DXPS assessed as inhibition constant in presence of pyruvateMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of his-tagged recombinant Escherichia coli W3110 DXPSMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine
Curated by ChEMBL
The Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataKi: 8.36E+4nMAssay Description:Uncompetitive inhibition of Escherichia coli DXPS assessed as inhibition constant in presence of fixed concentration of GAP and varying concentration...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 9.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 9.84E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair


3D Structure (crystal)




































