Report error Found 275 Enz. Inhib. hit(s) with Target = '1,3-beta-glucan synthase'
Affinity DataEC50: 1.20E+4nMAssay Description:Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataEC50: 4.60E+3nMAssay Description:Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 2.43E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in HEK cell assessed as increase in glycine-induced calcium influxMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2A receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
Affinity DataEC50: 2.80E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+5nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.117nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.171nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.877nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
