BDBM92348 1,4-Hybrid, 6

SMILES CN(C)CCCC(=O)Nc1ccc2ncnc(Nc3ccc(NC(=O)Nc4cc(nn4-c4cccc(N)c4)C(C)(C)C)cc3)c2c1

InChI Key InChIKey=WIVSUJLYDAGUDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92348   

TargetTyrosine-protein kinase ABL1(Human)
Technical University of Dortmund

Curated by ChEMBL
LigandPNGBDBM92348(1,4-Hybrid, 6)
Affinity DataIC50: 124nMAssay Description:Inhibition of human wild-type ABL (Ser229 to Gln513)-mediated phosphorylation of biotinylated poly-Glu-Tyr expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Technical University of Dortmund

Curated by ChEMBL
LigandPNGBDBM92348(1,4-Hybrid, 6)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of chicken wild-type cSRC (251 to 533)-mediated phosphorylation of biotinylated poly-Glu-Tyr expressed in Escherichia coli BL21(DE3) prein...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPutative glycogen synthase kinase 3 alpha(Corn smut fungus)
Technische UniversitÄT Dortmund

LigandPNGBDBM92348(1,4-Hybrid, 6)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of UmGSK3 by kinase inhibitors.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische UniversitÄT Dortmund

LigandPNGBDBM92348(1,4-Hybrid, 6)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of UmGSK3 by kinase inhibitors.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed