BDBM92293 uPa_18

SMILES NC(=N)c1ccc2cc(ccc2c1)C#Cc1ccc2CNCCc2c1

InChI Key InChIKey=ACKRFKIRNILEQJ-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 92293   

TargetUrokinase-type plasminogen activator [179-424,C299A,N323Q](Human)
D3R/Abbott

LigandBDBM92293(uPa_18)Copy SMILESCopy InChI

Affinity DataKi:  58.8nMAssay Description:Photometric_Method1More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails
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PDB3D Structure (crystal)
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TargetUrokinase-type plasminogen activator(Human)
Csar

LigandBDBM92293(uPa_18)Copy SMILESCopy InChI

Affinity DataKi:  59nM ΔG°:  -9.86kcal/molepH: 7.4 T: 2°CAssay Description:Abbott uPA__Urokinase Human - Ki(uM)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy reaction URL

TargetUrokinase-type plasminogen activator(Human)
Csar

LigandBDBM92293(uPa_18)Copy SMILESCopy InChI

Affinity DataKi:  63nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL