BDBM7627 2,4-bis anilino pyrimidine deriv. 23::5-bromo-2-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4-N-phenylpyrimidine-2,4-diamine

SMILES CN(C)CC(O)COc1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1

InChI Key InChIKey=MEIJADBULOETOV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7627   

LigandPNGBDBM7627(5-bromo-2-N-{4-[3-(dimethylamino)-2-hydroxypropoxy...)
Affinity DataIC50: 100nMAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM7627(5-bromo-2-N-{4-[3-(dimethylamino)-2-hydroxypropoxy...)
Affinity DataIC50: 300nMAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)